Results 31 to 40 of about 907,448 (315)

Teaching focused echocardiography for rheumatic heart disease screening

Annals of Pediatric Cardiology, 2015
Screening for rheumatic heart disease (RHD) requires workers skilled in echocardiography, which typically involves prolonged, specialized training. Task shifting echocardiographic screening to nonexpert health workers may be a solution in settings with ...
Daniel Engelman, Joseph H Kado, Bo Reményi, Samantha M Colquhoun, Caroline Watson, Sera C Rayasidamu, Andrew C Steer   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Sensitivity and Specificity of Portable Hearing Screening in Middle-Aged and Older Adults

International Archives of Otorhinolaryngology, 2014
Introduction Hearing screening allows the identification of individuals with hearing loss. Aim To determine the sensitivity and specificity of a portable hearing screening device in middle-aged and older adults using the manufacturer scoring
Carolina Louise Cardoso, Ângelo José Gonçalves Bós, Andréa Krüger Gonçalves, Maira Rozenfeld Olchik, Leticia Sousa Flores, Bruna Macagnin Seimetz, Magda Aline Bauer, Patricia Pérez Coradini, Adriane Ribeiro Teixeira   +8 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cost Effectiveness Associated with Helicobacter pylori Screening and Eradication in Patients Taking Nonsteroidal Anti-Inflammatory Drugs and/or Aspirin

Gut and Liver, 2013
Background/AimsThis study was performed to investigate the cost effectiveness of Helicobacter pylori screening/eradication in South Korean patients treated with nonsteroidal anti-inflammatory drugs (NSAIDs) and/or aspirin.Methods : A decision Markov ...
doaj   +1 more source

Performance of a one-step fecal sample-based test for diagnosis of Helicobacter pylori infection in primary care and mass screening settings

Journal of the Formosan Medical Association, 2014
An alternative screening test is needed to efficiently eradicate Helicobacter pylori from a population with prevalent upper gastrointestinal lesions. We evaluated the performance of a new one-step fecal test for H. pylori for diagnosis of H.
Yi-Chia Lee, Ping-Huei Tseng, Jyh-Ming Liou, Mei-Jyh Chen, Chien-Chuan Chen, Chia-Hung Tu, Tsung-Hsien Chiang, Han-Mo Chiu, Chien-Fang Lai, Jhon-Chun Ho, Ming-Shiang Wu   +10 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Lack of consensus in calculation of interval cancer rates for cervical cancer screening

Acta Obstetricia et Gynecologica Scandinavica
Introduction In 2018, nondisclosure of results of retrospective audits of cytology in interval cancers precipitated a crisis in the Irish national cervical screening programme.
Patricia Fitzpatrick, Therese Mooney, Yvonne Williams, Caroline Mason Mohan, Jesper Bonde, Julia Gao, Andrzej Nowakowski, Annemie Haelens, Urska Ivanus, Maiju Pankakoski, Tina Karapetyan, Noirin E. Russell   +11 more
doaj   +1 more source

Magnetic confinement and screening masses [PDF]

Physics Letters B, 1995
Confined and deconfined phases are defined through nonperturbative correlators and nonperturbative background perturbation theory is used to compute the critical temperature $T_c$ and spatial string tension. Taking evolution along one of the spatial axes the set of Hamiltonians $H(n_1,n_2)$ with different Matsubara frequencies is obtained.
Gubankova, E. L., Simonov, Yu. A.
openaire   +2 more sources