Results 91 to 100 of about 5,492,223 (387)

Position-sensitive ion detection in precision Penning trap mass spectrometry [PDF]

open access: yes, 2009
A commercial, position-sensitive ion detector was used for the first time for the time-of-flight ion-cyclotron resonance detection technique in Penning trap mass spectrometry.
A. Czasch   +43 more
core   +2 more sources

Inductively Coupled Plasma Mass Spectrometry: Introduction to Analytical Aspects.

open access: yesClinical biochemist reviews, 2019
Inductively coupled plasma mass spectrometry (ICP-MS) is an analytical technique that can be used to measure elements at trace levels in biological fluids.
Scott Wilschefski, Matthew Baxter
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Spatial Metabolomics Approach Reveals the Pharmacodynamic Substances and Mechanism of Panax ginseng in Alzheimer’s Disease Mice

open access: yesZhipu Xuebao
Panax ginseng, a venerable herb in traditional Chinese medicine, boasts a rich history of usage in the treatment of dementia, particularly in its various manifestations.
Yu-ting FAN   +5 more
doaj   +1 more source

Peaks detection and alignment for mass spectrometry data [PDF]

open access: yes, 2010
The goal of this paper is to review existing methods for protein mass spectrometry data analysis, and to present a new methodology for automatic extraction of significant peaks (biomarkers). For the pre-processing step required for data from MALDI-TOF or
Antoniadis, Anestis   +2 more
core   +2 more sources

MS²PIP: a tool for MS/MS peak intensity prediction [PDF]

open access: yes, 2013
Motivation: Tandem mass spectrometry provides the means tomatch mass spectrometry signal observations with the chemical entities that generated them. The technology produces signal spectra that contain information about the chemical dissociation pattern ...
Degroeve, Sven, Martens, Lennart
core   +2 more sources

Missing Value Imputation Approach for Mass Spectrometry-based Metabolomics Data

open access: yesScientific Reports, 2018
Missing values exist widely in mass-spectrometry (MS) based metabolomics data. Various methods have been applied for handling missing values, but the selection can significantly affect following data analyses.
Runmin Wei   +6 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

A solid-state infrared laser for two-step desorption–ionization processes in single-particle mass spectrometry [PDF]

open access: yesAtmospheric Measurement Techniques
Recent advancements in single-particle mass spectrometry (SPMS) have enabled the detection of aromatic hydrocarbons at the individual particle level in conjunction with inorganic/refractory particle components.
M. Schmidt   +24 more
doaj   +1 more source

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