Results 111 to 120 of about 5,293,958 (301)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

An analytical pipeline for MALDI in-source decay mass spectrometry imaging

, 2011
peer reviewedIn-source decay (ISD) fragmentation as combined with matrix-assisted laser desorption/ionization (MALDI) mass spectrometry allows protein sequencing directly from mass spectra.
Debois, Delphine, De Pauw, Edwin, Gabriel Mazzucchelli, Virginie Bertrand, De Pauw-Gillet, Marie-Claire, Edwin De Pauw, Zimmerman, Tyler, Delphine Debois, Tyler A. Zimmerman, Mazzucchelli, Gabriel, Marie-Claire De Pauw-Gillet, Bertrand, Virginie   +11 more
core   +1 more source

Multimodal Molecular Imaging combining Raman Spectroscopy and Mass Spectrometry for the study of biological samples

, 2019
Biological samples such as tissues, cells or microbial communities including biofilms are intricate molecular systems. Their complexity is mainly expressed by the heterogeneity of their microstructure, both in terms of spatial molecular distribution and ...
Bertrand, Virginie, Müller, Wendy, Malherbe, Cédric, Eppe, Gauthier   +3 more
core   +1 more source

Pharmacometabolomics and mass spectrometry imaging approach to reveal the neurochemical mechanisms of Polygala tenuifolia

Journal of Pharmaceutical Analysis
Polygala tenuifolia, commonly known as Yuanzhi (YZ) in Chinese, has been shown to possess anti-insomnia properties. However, the material basis and the mechanism underlying its sedative-hypnotic effects remain unclear.
Qian Li, Jinpeng Bai, Yuxue Ma, Yu Sun, Wenbin Zhou, Zhaoying Wang, Zhi Zhou, Zhonghua Wang, Yanhua Chen, Zeper Abliz   +9 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

imzML: Imaging Mass Spectrometry Markup Language: A Common Data Format for Mass Spectrometry Imaging

, 2010
International audienceImaging mass spectrometry is the method of scanning a sample of interest and generating an “image” of the intensity distribution of a specific analyte.
Heeren, Ron M. A., Hester, Alfons, Bernhard Spengler, Jean-Pierre Both, Both, Jean-Pierre, Stoeckli, Markus, Ron M. A. Heeren, Spengler, Bernhard, Römpp, Andreas, Thorsten Schramm, Alfons Hester, Schramm, Thorsten, Andreas Römpp, Markus Stöckli, Klinkert, Ivo, Ivo Klinkert   +15 more
core   +1 more source

How Does the Sweet Violet (Viola odorata L.) Fight Pathogens and Pests – Cyclotides as a Comprehensive Plant Host Defense System

Frontiers in Plant Science, 2018
Cyclotides are cyclic plant polypeptides of 27–37 amino acid residues. They have been extensively studied in bioengineering and drug development contexts. However, less is known about the relevance of cyclotides for the plants producing them.
Blazej Slazak, Blazej Slazak, Małgorzata Kapusta, Adam A. Strömstedt, Aneta Słomka, Marta Krychowiak, Mohammadreza Shariatgorji, Per E. Andrén, Jerzy Bohdanowicz, Elżbieta Kuta, Ulf Göransson   +10 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Method development for correlating lipid molecular information with anatomy in C. elegans

Scientific Reports
Caenorhabditis elegans (C. elegans) is an important model organism for studying fat storage and lipid metabolism. Mass-spectrometry imaging (MSI) is an emerging technology for mapping the spatial distribution of lipids.
Sara Mandic, Bryn Flinders, Michiel Vandenbosch, Akane Ohta, Atsushi Kuhara, Ron M. A. Heeren, Masazumi Fujiwara   +6 more
doaj   +1 more source

A laboratory-friendly protocol for freeze-drying sample preparation in ToF-SIMS single-cell imaging

Frontiers in Chemistry
ToF-SIMS is a high spatial resolution imaging technique for cellular or subcellular analysis of biological samples. Accurate molecular data in single-cell studies depend on proper cell morphology and chemical integrity, highlighting the importance of ...
Xiujuan Shi, Mingru Liu, Yue Qi, Hongzhe Ma, Zhaoying Wang, Zhaoying Wang, Yanhua Chen, Yanhua Chen, Zeper Abliz   +8 more
doaj   +1 more source