Results 211 to 220 of about 332,432 (245)

Imaging Mass Spectrometry

Proceedings, annual meeting, Electron Microscopy Society of America, 1982
In the last few years a number of imaging analytical instrumental techniques have been developed: TEM, SEM, STEM, EM, SAM, RBS, ISS, PIXE, and SIMS. While all of these techniques can produce images describing sample morphology, some also produce chemical and elemental images. A few can produce images containing three-dimensional topographic information
Adam J. Patkin, George H. Morrison
openaire   +1 more source

Mass Spectrometry Imaging (MSI)

Mass Spectrometry Imaging (MSI) stands out as a pivotal tool in food analysis to directly visualize the spatial distribution of specific compounds within intricate food matrices. Despite notable advantages, such as label-free analysis and unparalleled spatial resolution, MSI faces challenges.
Caponigro, V., Salviati, E., Olarini, A., Campiglia, P.   +3 more
openaire   +1 more source

Imaging mass spectrometry statistical analysis

Journal of Proteomics, 2012
Imaging mass spectrometry is increasingly used to identify new candidate biomarkers. This clinical application of imaging mass spectrometry is highly multidisciplinary: expertise in mass spectrometry is necessary to acquire high quality data, histology is required to accurately label the origin of each pixel's mass spectrum, disease biology is ...
Jones, E.A., Deininger, S.O., Hogendoorn, P.C.W., Deelder, A.M., McDonnell, L.A.   +4 more
openaire   +3 more sources

Imaging mass spectrometry for lipidomics

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2011
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is a powerful tool that enables the simultaneous detection and identification of biomolecules in analytes. MALDI-imaging mass spectrometry (MALDI-IMS) is a two-dimensional MALDI-MS technique used to visualize the spatial distribution of biomolecules without extraction ...
Naoko, Goto-Inoue, Takahiro, Hayasaka, Nobuhiro, Zaima, Mitsutoshi, Setou   +3 more
openaire   +2 more sources

Imaging Mass Spectrometry of Glycolipids

2010
Mass spectrometry (MS) is an analytical technique that separates ionized molecules using differences in their mass, and can be used to determine the structure of the molecules. Matrix-assisted laser desorption/ionization (MALDI) is one of the most commonly used ionization methods for this procedure.
Naoko, Goto-Inoue, Takahiro, Hayasaka, Mitsutoshi, Setou   +2 more
openaire   +2 more sources

Mass microscopy: high-resolution imaging mass spectrometry

Journal of Electron Microscopy, 2010
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a technique that localizes the spatial distribution of molecules and identifies structures by their molecular mass signatures. Recently, the resolution of MALDI-IMS has been up to microscopic level. MALDI-IMS does not need either separation or purification procedures
Mitsutoshi, Setou, Nobuya, Kurabe
openaire   +2 more sources

DESI Mass Spectrometry Imaging (MSI)

2017
Desorption Electrospray Ionization (DESI) mass spectrometry is a technique that allows chemical information to be obtained directly from a wide range of surfaces. Using a 2D stage, DESI can be implemented in an imaging mode whereby MS spectra are collected by rastering the spray across the whole surface.
Emmanuelle, Claude, Emrys A, Jones, Steven D, Pringle   +2 more
openaire   +2 more sources

Imaging with Mass Spectrometry

Chemical Reviews, 1999
M L, Pacholski, N, Winograd
openaire   +2 more sources

MALDI-Imaging Mass Spectrometry on Tissues

2014
Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF)-profiling and imaging mass spectrometry (MSI) are promising technologies for measuring hundreds of different molecules directly on tissues. For instance, small molecules, drugs and their metabolites, endogenous lipids, carbohydrates and complex peptides/proteins can be measured at ...
MAININI, VERONICA, Lalowski, M, Gotsopoulos, A, Bitsika, V, Baumann, M, MAGNI, FULVIO   +5 more
openaire   +3 more sources

Mass Spectrometry Imaging of Cholesterol

2019
Mass spectrometry imaging (MSI) has evolved as a significant tool to map biomolecules in situ without tags. This chapter describes advancements in mass spectrometry imaging technology and applications focused on mapping cholesterol. Secondary ion mass spectrometry (SIMS), matrix-assisted laser desorption/ionization (MALDI), and desorption electrospray (
openaire   +2 more sources