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Imaging mass spectrometry in microbiology [PDF]

open access: yesNature Reviews Microbiology, 2011
Imaging mass spectrometry tools allow the two-dimensional visualization of the distribution of trace metals, metabolites, surface lipids, peptides and proteins directly from biological samples without the need for chemical tagging or antibodies, and are becoming increasingly useful for microbiology applications.
Jeramie D Watrous, Pieter C Dorrestein
exaly   +3 more sources

Mass Spectrometry Imaging of Metabolites

2018
Mass spectrometry imaging (MSI) is a technique which is gaining increasing interest in biomedical research due to its capacity to visualize molecules in tissues. First applied to the field of clinical proteomics, its potential for metabolite imaging in biomedical studies is now being recognized.
Balluff, Benjamin, McDonnell, Liam A.
openaire   +3 more sources

Imaging mass spectrometry for lipidomics

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2011
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is a powerful tool that enables the simultaneous detection and identification of biomolecules in analytes. MALDI-imaging mass spectrometry (MALDI-IMS) is a two-dimensional MALDI-MS technique used to visualize the spatial distribution of biomolecules without extraction ...
Naoko, Goto-Inoue   +3 more
openaire   +2 more sources

Imaging Mass Spectrometry of Glycolipids

2010
Mass spectrometry (MS) is an analytical technique that separates ionized molecules using differences in their mass, and can be used to determine the structure of the molecules. Matrix-assisted laser desorption/ionization (MALDI) is one of the most commonly used ionization methods for this procedure.
Naoko, Goto-Inoue   +2 more
openaire   +2 more sources

Imaging Mass Spectrometry

2010
Imaging Mass Spectrometry (IMS) is a powerful analytical technology that provides both molecular and spatial information from a single sample. This chapter provides a brief history of Imaging Mass Spectrometry, including early work with secondary ion mass spectrometry (SIMS) and laser desorption/ionization (LDI) techniques.
Marilyn E. Carroll   +68 more
  +4 more sources

Structurally Selective Imaging Mass Spectrometry by Imaging Ion Mobility-Mass Spectrometry

2010
This chapter describes the utility of structurally based separations combined with imaging mass spectrometry (MS) by ion mobility-MS (IM-MS) approaches. The unique capabilities of combining rapid (mus-ms) IM separations with imaging MS are detailed for an audience ranging from new to potential practitioners in IM-MS technology.
John A, McLean   +2 more
openaire   +2 more sources

Imaging Mass Spectrometry

Applied Spectroscopy Reviews, 2011
Abstract Mass spectrometry has been a valuable resource in science for decades. The ability to know exact masses of analytes allows for a more precise knowledge of the composition of materials. The technique has evolved to allow analysis of increasing numbers compounds in increasingly complex environments.
Joseph Smeal, Charles L. Wilkins
openaire   +1 more source

Mass Spectrometry Imaging of Cholesterol

2019
Mass spectrometry imaging (MSI) has evolved as a significant tool to map biomolecules in situ without tags. This chapter describes advancements in mass spectrometry imaging technology and applications focused on mapping cholesterol. Secondary ion mass spectrometry (SIMS), matrix-assisted laser desorption/ionization (MALDI), and desorption electrospray (
openaire   +2 more sources

Mass Spectrometry Imaging

2010
Introductory Reviews and Tutorials.- Imaging Mass Spectrometry: Viewing the Future.- A Mass Spectrometry Primer for Mass Spectrometry Imaging.- Imaging of Metals, Metalloids, and Non-metals by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) in Biological Tissues.- Protocols for MS Imaging of Distribution of Small Molecules ...
Michael M. Morgan   +129 more
openaire   +2 more sources

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