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MALDI-Imaging Mass Spectrometry on Tissues
2014Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF)-profiling and imaging mass spectrometry (MSI) are promising technologies for measuring hundreds of different molecules directly on tissues. For instance, small molecules, drugs and their metabolites, endogenous lipids, carbohydrates and complex peptides/proteins can be measured at ...
MAININI, VERONICA +5 more
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Proceedings, annual meeting, Electron Microscopy Society of America, 1982
In the last few years a number of imaging analytical instrumental techniques have been developed: TEM, SEM, STEM, EM, SAM, RBS, ISS, PIXE, and SIMS. While all of these techniques can produce images describing sample morphology, some also produce chemical and elemental images. A few can produce images containing three-dimensional topographic information
Adam J. Patkin, George H. Morrison
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In the last few years a number of imaging analytical instrumental techniques have been developed: TEM, SEM, STEM, EM, SAM, RBS, ISS, PIXE, and SIMS. While all of these techniques can produce images describing sample morphology, some also produce chemical and elemental images. A few can produce images containing three-dimensional topographic information
Adam J. Patkin, George H. Morrison
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Mass Spectrometry Imaging (MSI)
Mass Spectrometry Imaging (MSI) stands out as a pivotal tool in food analysis to directly visualize the spatial distribution of specific compounds within intricate food matrices. Despite notable advantages, such as label-free analysis and unparalleled spatial resolution, MSI faces challenges.Caponigro, V. +3 more
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Perspectives in imaging using mass spectrometry
Chem. Commun., 2011Imaging mass spectrometry (MS) allows a remarkable range of measurements including diagnosis of disease state of tissue based on detailed information on its chemical constituents, especially lipids and proteins. The recent emergence of ambient ionization allows imaging in the open environment without sample preparation.
Allison L, Dill +3 more
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Applications of Mass Spectrometry Imaging to Cancer
2017Pathologists play an essential role in the diagnosis and prognosis of benign and cancerous tumors. Clinicians provide tissue samples, for example, from a biopsy, which are then processed and thin sections are placed onto glass slides, followed by staining of the tissue with visible dyes.
Arentz, G. +7 more
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Imaging Mass Spectrometry: Viewing the Future
2010Imaging mass spectrometry (IMS) technology is an effective tool that is able to assess complex molecular mixtures in cells, tissues, or other sample types with high chemical specificity, allowing concurrent analysis of a variety of molecular species in a wide mass range, from small metabolites to large macromolecules such as proteins.
Sarah A, Schwartz, Richard M, Caprioli
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Lipidomics and Imaging Mass Spectrometry
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2011Robert C, Murphy, Alfred H, Merrill
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Quantitative Mass Spectrometry Imaging of Biological Systems
Annual Review of Physical Chemistry, 2021Daisy Unsihuay +2 more
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Molecular imaging by mass spectrometry — looking beyond classical histology
Nature Reviews Cancer, 2010Kristina Schwamborn, Richard M Caprioli
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MALDI Imaging of Lipid Biochemistry in Tissues by Mass Spectrometry
Chemical Reviews, 2011Karin A Zemski Berry +2 more
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