Results 11 to 20 of about 1,058,705 (300)

Constraining Exoplanet Mass from Transmission Spectroscopy [PDF]

Science, 2013
Determination of an exoplanet's mass is a key to understanding its basic properties, including its potential for supporting life. To date, mass constraints for exoplanets are predominantly based on radial velocity (RV) measurements, which are not suited ...
de Wit, Julien, Seager, Sara
core   +3 more sources

Site-Specific Structural Changes in Long-Term-Stressed Monoclonal Antibody Revealed with DEPC Covalent-Labeling and Quantitative Mass Spectrometry

Pharmaceuticals, 2023
Studies of structural changes in mAbs under forced stress and storage conditions are essential for the recognition of degradation hotspots, which can be further remodeled to improve the stability of the respective protein.
Manasi Gaikwad, Florian Richter, Rabea Götz, Aline Dörrbaum, Lena Schumacher, Jason Tonillo, Christian Frech, Roland Kellner, Carsten Hopf   +8 more
doaj   +1 more source

Measurement of the Filling Degree and Droplet Size of Individual Double Emulsion Droplets Using Raman Technologies

Chemosensors, 2022
Double emulsions arouse great interest in various industries due to their ability to encapsulate value-adding ingredients. However, they tend to be unstable due to their complex structure.
Thomas Hufnagel, Richard Stoy, Matthias Rädle, Heike P. Karbstein   +3 more
doaj   +1 more source

Spatial probabilistic mapping of metabolite ensembles in mass spectrometry imaging

Nature Communications, 2023
Spatial visualization of metabolites in tissues via mass spectrometry imaging can be prone to user perception bias. Here, the authors report the computational framework moleculaR that introduces probabilistic data-dependent molecular mapping of nonrandom
Denis Abu Sammour, James L. Cairns, Tobias Boskamp, Christian Marsching, Tobias Kessler, Carina Ramallo Guevara, Verena Panitz, Ahmed Sadik, Jonas Cordes, Stefan Schmidt, Shad A. Mohammed, Miriam F. Rittel, Mirco Friedrich, Michael Platten, Ivo Wolf, Andreas von Deimling, Christiane A. Opitz, Wolfgang Wick, Carsten Hopf   +18 more
doaj   +1 more source

Film Thickness and Glycerol Concentration Mapping of Falling Films Based on Fluorescence and Near-Infrared Technique

Micromachines, 2022
Falling film evaporation processes involve high fluid velocities with continuous variations in local film thickness, fluid composition, and viscosity.
Isabel Medina, Stephan Scholl, Matthias Rädle   +2 more
doaj   +1 more source

Monitoring of Osmotic Swelling Induced Filling Degree Changes in WOW Double Emulsions Using Raman Technologies

Chemosensors, 2023
Due to their nested structure, double emulsions have the potential to encapsulate value-adding substances until their application, making them of interest to various industries.
Thomas Hufnagel, Nico Leister, Richard Stoy, Matthias Rädle, Heike P. Karbstein   +4 more
doaj   +1 more source

Device-Controlled Microcondensation for Spatially Confined On-Tissue Digests in MALDI Imaging of N-Glycans

Pharmaceuticals, 2022
On-tissue enzymatic digestion is a prerequisite for MALDI mass spectrometry imaging (MSI) and spatialomic analysis of tissue proteins and their N-glycan conjugates.
Annabelle Fülöp, Christian Marsching, Frederik Barka, Yasemin Ucal, Pauline Pfänder, Christiane A. Opitz, Günes Barka, Carsten Hopf   +7 more
doaj   +1 more source

In vivo characterization of the bacterial intramembrane-cleaving protease RseP using the heme binding tag-based assay iCliPSpy

Communications Biology, 2023
iCLiPSpy is a simple assay to identify residues important for substrate binding and activity of intramembrane-cleaving proteases (I-CLiPs) in vivo and can be adapted to a screening assay for I-CLiP inhibitor or activator discovery.
Thomas Kupke, Rabea M. Götz, Florian M. Richter, Rainer Beck, Fabio Lolicato, Walter Nickel, Carsten Hopf, Britta Brügger   +7 more
doaj   +1 more source

Design of a Multimodal Imaging System and Its First Application to Distinguish Grey and White Matter of Brain Tissue. A Proof-of-Concept-Study

Applied Sciences, 2021
Multimodal imaging gains increasing popularity for biomedical applications. This article presents the design of a novel multimodal imaging system. The centerpiece is a light microscope operating in the incident and transmitted light mode.
Annabell Heintz, Sebastian Sold, Felix Wühler, Julia Dyckow, Lucas Schirmer, Thomas Beuermann, Matthias Rädle   +6 more
doaj   +1 more source

The Anatomy of the Internet of Digital Twins: A Symbiosis of Agent and Digital Twin Paradigms Enhancing Resilience (Not Only) in Manufacturing Environments

Machines, 2023
Due to the growing environmental and geopolitical challenges nowadays, which are causing supply chain complications, industry and society are facing significant new objections. As a complement and extension to the technology-driven premises of Industry 4.
Joel Lehmann, Andreas Lober, Tim Häußermann, Alessa Rache, Lisa Ollinger, Hartwig Baumgärtel, Julian Reichwald   +6 more
doaj   +1 more source