FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Disentangle a Complex MALDI TOF Mass Spectrum of Polyethylene Glycols into Three Separate Spectra via Selective Formation of Protonated Ions and Sodium or Potassium Adducts. [PDF]
J Am Soc Mass Spectrom, 2022 Lou X +3 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Regge trajectories and mass spectrum of heavy tetraquarks
European Physical Journal C: Particles and FieldsIn this work, we calculated the masses of the ground and radial excited states of heavy tetraquarks in the framework of the nonrelativistic quark model for two wave states nS and nP.
A. Ghasempour, N. Tazimi, M. Monemzadeh
doaj +1 more source
Probabilistic framework for integration of mass spectrum and retention time information in small molecule identification. [PDF]
Bioinformatics, 2021 Bach E, Rogers S, Williamson J, Rousu J.
europepmc +1 more source
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
Mass spectrum & linear perturbations of ghost-free multi-spin-2 theory
Journal of High Energy PhysicsMotivated by the spin-2 nature of gravity, we consider a theory of N $$ \mathcal{N} $$ interacting spin-2 fields, formulated in terms of vielbeins, which has been argued to be free of Boulware-Deser ghost instabilities. This is the only known such theory
J. Flinckman, S. F. Hassan
doaj +1 more source
SIMSI-Transfer: Software-Assisted Reduction of Missing Values in Phosphoproteomic and Proteomic Isobaric Labeling Data Using Tandem Mass Spectrum Clustering. [PDF]
Mol Cell Proteomics, 2022 Hamood F +4 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Selected Ion Monitoring Using Low-Cost Mass Spectrum Detectors Provides a Rapid, General, and Accurate Method for Enantiomeric Excess Determination in High-Throughput Experimentation. [PDF]
ACS Catal, 2022 Korch KM +5 more
europepmc +1 more source