Results 121 to 130 of about 2,087,811 (325)

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Constraining the Effective Mass of Majorana Neutrino with Sterile Neutrino Mass for Inverted Ordering Spectrum

open access: yesAdvances in High Energy Physics, 2019
Inspired by the experimental anomalies in neutrino physics and recent oscillation data from short baseline and another neutrino experiment, the realization of one extra neutrino flavor seems to be favoring.
Jaydip Singh
doaj   +1 more source

Advanced parental age and risk of positive autism spectrum disorders screening

open access: yesInternational Journal of Preventive Medicine, 2019
Background: Autism Spectrum Disorder (ASD) is a life -long neurodevelopmental disorder and significantly influences the quality of life in children. The screening of ASD in children aged between 16-30 months to early detection and early intervention for ...
Leila Manzouri   +3 more
doaj   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

A graph-based filtering method for top-down mass spectral identification

open access: yesBMC Genomics, 2018
Background Database search has been the main approach for proteoform identification by top-down tandem mass spectrometry. However, when the target proteoform that produced the spectrum contains post-translational modifications (PTMs) and/or mutations, it
Runmin Yang, Daming Zhu
doaj   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

open access: yesFEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

The Higgs mass and natural supersymmetric spectrum from the landscape

open access: yesPhysics Letters B, 2016
In supersymmetric models where the superpotential μ term is generated with μ≪msoft (e.g. from radiative Peccei–Quinn symmetry breaking or compactified string models with sequestration and stabilized moduli), and where the string landscape 1.
Howard Baer   +3 more
doaj   +1 more source

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