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Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Enhancing MALDI time-of-flight mass spectrometer performance through spectrum averaging. [PDF]
Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometers are simple and robust mass spectrometers used for analysis of biologically relevant molecules in diverse fields including pathogen identification, imaging mass ...
Morgan Mitchell+3 more
doaj +1 more source
SCOPUS: ar.j ; info:eu-repo/semantics ...
Englert, François+2 more
openaire +2 more sources
The possibility has been pointed out that if the relative parity between nucleons and particles is assumed to be odd, the lowest order self-energies of baryons coming from the charge-independent strong interaction give the observed baryon mass level ordering. Schwinger also suggested such a level splitting in a discussion of the isospace symmetry.
K. Shimoura, H. Katsumori
openaire +2 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Top-quark mass from the diphoton mass spectrum
We calculate the $$gg\rightarrow \gamma \gamma $$ g g → γ γ amplitude by including the $$t\bar{t}$$ t t ¯ bound-state effects near their mass threshold.
Sayaka Kawabata, Hiroshi Yokoya
doaj +1 more source
The Mass-Spectrum of Copper [PDF]
THE number of elements of which the isotopic nature has been determined is now large enough to give considerable weight to statistical relations. Among elements of odd atomic number two definite empirical rules stand out. The first is that none of them consists of more than two isotopes. This has no exception so far.
openaire +1 more source
Golgi-targeting viscosity probe for the diagnosis of Alzheimer’s disease
Early diagnosis and intervention of Alzheimer’s disease (AD) are particularly important to delay the pathological progression. Although fluorescent probes have been widely employed for investigating and diagnosing AD, their biological applications are ...
Wenjing Wu+6 more
doaj +1 more source
Sensory Evaluation of Interference Suppression in Odor Reproduction Using Mass Spectrometry
Odor sensing enables us to sense odorant stimuli. This sensation causes a deep subconscious response in humans in various ways and represents an indispensable sensation in daily life.
Dani Prasetyawan+2 more
doaj +1 more source