Results 111 to 120 of about 2,292,783 (294)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Liquid Crystal‐Driven Chemical Feeding Accelerates Condensation Reactions in Droplet Microreactors

Advanced Science
Droplet microreactors have gained significant attention as confined spaces for chemical reactions, offering enhanced reaction rates and control. However, the impact of mass transfer induced by chemical feeding within these microreactors remains largely ...
Yang Xu, Alan H. Weible, Meng Zhang, Weichen Deng, Jen‐Chun Fang, Xiaoguang Wang   +5 more
doaj   +1 more source

MULTI-SPECIES MULTI-PHYSICS MODELING AND VALIDATION OF HYDRODYNAMIC ELECTROCHEMICAL SYSTEM FOR USED NUCLEAR FUEL [PDF]

, 2018
Department of Nuclear EngineeringAccurate predictions of processes in hydrodynamic electrochemical systems require an understanding of both the surface electrochemical reactions and the bulk mass transport. Complete coupling of electrochemistry and fluid
Kang, Dokyu
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Influence of the microvasculature on oxygen transport in human brain tissue [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Payne, SJ, Su, SW   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Investigation Perspectives of Dynamics of Tank Vehicles for Liquid Loads

Механика машин, механизмов и материалов, 2007
It is analysed a current state and investigation perspectives of dynamics truck and rail tank vehicles. There are resulted equations presenting movement of considered system members.
A.O. Shimanovsky, Yu.M. Pleskachevsky, M.S. Vysotsky   +2 more
doaj  

Application of remote sensing in estimating evapotranspiration in the Platte river basin [PDF]

A 'resistance model' and a mass transport model for estimating evapotranspiration (ET) were tested on large fields of naturally subirrigated alfalfa. Both models make use of crop canopy temperature data.
Blad, B. L., Rosenberg, N. J.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Mass variation observing system by high low inter-satellite links (MOBILE) – a new concept for sustained observation of mass transport from space

Journal of Geodetic Science, 2019
As changes in gravity are directly related to mass variability, satellite missions observing the Earth’s time varying gravity field are a unique tool for observing mass transport processes in the Earth system, such as the water cycle, rapid changes in ...
Pail R., Bamber J., Biancale R., Bingham R., Braitenberg C., Eicker A., Flechtner F., Gruber T., Güntner A., Heinzel G., Horwath M., Longuevergne L., Müller J., Panet I., Savenije H., Seneviratne S., Sneeuw N., van Dam T., Wouters B.   +18 more
doaj   +1 more source