Results 101 to 110 of about 2,292,783 (294)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Transport Characteristics of Small Molecules Diffusing near Deforming Blood Cells
ComputationUnderstanding the transport of small molecules such as oxygen in biological systems requires knowledge about how molecules dynamically interact with these molecules.
Stephanie Nix
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Mass and Momentum Turbulent Transport Experiments [PDF]
An experimental study of mixing downstream of axial and swirling coaxial jets is being conducted to obtain data for the evaluation and improvement of turbulent transport models currently employed in a variety of computational procedures used throughout ...
Johnson, B. V., Roback, R.
core +1 more source
Factorised Steady States in Mass Transport Models on an Arbitrary Graph
, 2006 We study a general mass transport model on an arbitrary graph consisting of $L$ nodes each carrying a continuous mass. The graph also has a set of directed links between pairs of nodes through which a stochastic portion of mass, chosen from a site ...
Evans M R +9 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
ChemElectroChemHydrogen transport in the anode of a proton‐exchange membrane fuel cell (PEMFC) has been studied with a modulation technique relating the hydrogen flow‐rate ( Q˜H2 ) and the faradaic current ( I˜ ), called Current‐modulated Hydrogen flow‐rate ...
Luis Duque +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Enhanced Oil Recovery by Polymer Flooding: Direct, Low-Cost Visualization in a Hele–Shaw Cell
Education Sciences, 2019 We designed a hands-on laboratory exercise to demonstrate why injecting an aqueous polymer solution into an oil reservoir (commonly known as “polymer flooding”) enhances oil production.
Yukie Tanino, Amer Syed
doaj +1 more source