Results 71 to 80 of about 2,277,334 (290)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

An overview of cracks and interfacial voids in membrane electrode assemblies in polymer electrolyte fuel cells

open access: yesJournal of Thermal Science and Technology, 2015
In this review, an overview of cracks and interfacial voids formed in membrane electrode assemblies in polymer electrolyte fuel cells is presented. State-of-the-art of findings on formation processes of the cracks and the voids are described together ...
Shohji TSUSHIMA, Shuichiro HIRAI
doaj   +1 more source

Regularization via Mass Transportation

open access: yes, 2017
Team Bart De ...
Shaéezadeh-Abadeh, Soroosh (author)   +2 more
openaire   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Bending of Three-Layer Elastic Core with Variable Stiff Shell

open access: yesМеханика машин, механизмов и материалов, 2008
The bending of three-layer elastic core with variable thickness of one of two stiff shells is considered. To describe kinematics of asymmetrical over thickness pack of the core the hypotheses of the broken normal are accepted.
Yu.M. Pleskachevsky, E.E. Starovoytova
doaj  

Slow Mass Transport and Statistical Evolution of An Atomic Gas Across the Superfluid-Mott Insulator Transition

open access: yes, 2010
We study transport dynamics of ultracold cesium atoms in a two-dimensional optical lattice across the superfluid-Mott insulator transition based on in situ imaging.
Chin, Cheng   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Vibration of Circular Metal-Polymeric Plates on an Elastic Foundation under Heat Stroke

open access: yesМеханика машин, механизмов и материалов, 2009
The axisymmetrical vibrations of elastic circular three-layer metal-polymeric plate on en elastic foundation ander heat stroke are explored. For the kinematics description asymmetrical on the thickness of package accepted hypothesises broken normal ...
Yu.M. Pleskachevsky   +3 more
doaj  

Mass transport by diffusion [PDF]

open access: yes
For the purpose of determining diffusion coefficients as required for electrodeposition studies and other applications, a diaphragm cell and an isothermal water bath were constructed. the calibration of the system is discussed.
Baird, James K.
core   +1 more source

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