Results 91 to 100 of about 3,550,191 (258)

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

Advanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang   +16 more
wiley   +1 more source

Knowledge, attitudes and practices on adolescent vaccination among parents, teachers and adolescents in Africa: a systematic review protocol [PDF]

, 2014
Background: Vaccines are the most successful and cost-effective public health interventions available to avert vaccine-preventable diseases and deaths. Despite progress in the field of adolescent health, many young people in Africa still get sick and die
Adebayo, Esther F, Kagina, Benjamin M., Abdullahi, Leila H., Benjamin M Kagina, Esther F Adebayo, Kagina, Benjamin M, Wiysonge, Charles S, Hussey, Gregory D, Gregory D Hussey, Leila H Abdullahi, Abdullahi, Leila H, Wiysonge, Charles S., Hussey, Gregory D., Cassidy, Tali, Charles S Wiysonge, Adebayo, Esther F., Tali Cassidy   +16 more
core   +2 more sources

Genetically Programmed Shape‐Morphing of Engineered Living Materials

Advanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker, Yuchen Liu, Miguel Baños, Rosanne Schmachtenberg, Mahmudul Hasan, Claudia Fink‐Straube, Luai R. Khoury, Wilfried Weber   +7 more
wiley   +1 more source

A Rapid Assessment of Covid-19 Vaccine Averted Mortality Modelling

Interdisciplinary Journal of Epidemiology and Public Health
Introduction: The ubiquitous use of COVID-19 vaccination during the pandemic makes it challenging to quantify its effect. While comparisons can be made over time (comparing outcomes by vaccination rate), most estimates rely on modeling using vaccine ...
Matthew Halma, Ramiz Ahmed-Man, Amrit Šorli, Christof Plothe   +3 more
doaj   +1 more source

7-Valent pneumococcal conjugate vaccination in England and Wales: is it still beneficial despite high levels of serotype replacement? [PDF]

, 2011
BACKGROUND: The UK introduced the 7-valent pneumococcal conjugate vaccine (PCV7) into the national vaccination program in September 2006. Previous modelling assumed that the likely impact of PCV7 on invasive pneumococcal disease (IPD) would be similar to
Nigel Gay, Andrews, Nick, George, Robert, Robert George, Gay Nigel, Miller, Elizabeth, George Robert, Pauline A Waight, Miller Elizabeth, Yoon Hong Choi, N. Gay, Choi, Yoon Hong, Pauline A. Waight, Andrews Nick, R. George, Nick Andrews, Waight Pauline A., Jit, Mark, Gay, Nigel, Jit Mark, Y.H. Choi, Choi Yoon Hong, Elizabeth Miller, M. Jit, P.A. Waight, Melegaro, Alessia, E. Miller, Mark Jit, N. Andrews, Waight, Pauline A, Melegaro Alessia, Alessia Melegaro   +31 more
core   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Detection and Comparison of Sow Serum Samples from Herds Regularly Mass Vaccinated with Porcine Reproductive and Respiratory Syndrome Modified Live Virus Using Four Commercial Enzyme-Linked Immunosorbent Assays and Neutralizing Tests

Veterinary Sciences
Porcine reproductive and respiratory syndrome virus (PRRSV) modified live virus (MLV) vaccination is used to control PRRSV. In China, farms conduct random sampling from sow herds every 4 to 6 months. They use the enzyme-linked immunosorbent assay (ELISA)
Chaosi Li, Gang Wang, Zhicheng Liu, Shuhe Fang, Aihua Fan, Kai Chen, Jianfeng Zhang   +6 more
doaj   +1 more source

Improving vaccine-related pain, distress or fear in healthy children and adolescents–a systematic search of patient-focused interventions

Human Vaccines & Immunotherapeutics, 2018
Objective: The WHO recently highlighted the need for research into potential interventions that can be used to mitigate pain during mass vaccinations, in addition to interventions specific for adolescents.
Vivian Y. Lee, Corinne Caillaud, Jacqueline Fong, Kate M. Edwards   +3 more
doaj   +1 more source

Coverage survey of Measles-Rubella mass vaccination campaign in a rural area in Tamil Nadu

Journal of Family Medicine and Primary Care, 2019
Background: In Tamil Nadu, where health indicators are above the national average and routine immunization coverage is >95%, the tepid response to Measles-Rubella (MR) mass vaccination campaign was unexpected. Several parents refused MR vaccine for their
Priyadharshini, Aliya Jasmine
doaj   +1 more source