Results 71 to 80 of about 3,550,191 (258)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Successful elimination of PRRS virus from an infected farrow-to-finish herd by vaccination

Veterinární Medicína, 2017
Porcine reproductive and respiratory syndrome (PRRS) virus represents a major threat to the swine industry worldwide. This study describes the transmission of a European strain of PRRS-1 to a pig farm leading to the spread of the virus to different age ...
M. Toman, V. Celer, J. Smola
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Yellow fever outbreak in a rural-urban mixed community of Espírito Santo, Brazil: epidemiological aspects

Revista Panamericana de Salud Pública, 2019
Objective. To describe the epidemiological aspects of an outbreak of yellow fever (YF) that occurred in the state of Espírito Santo, Brazil, from 1 January 2017 – 31 July 2017. Methods.
Tálib Moysés Moussallem, Caroline Gava, Karla Spandl Ardisson, Clemilda Soares Marques, Giselle Calmon Graceli, Aline da Penha Valadares Koski, Gilton Luiz Almada, Alexandre Rodrigues da Silva, Fernando Antonio Alves de Jesus, Gilsa Aparecida Pimenta Rodrigues, Theresa Cristina Cardoso da Silva   +10 more
doaj   +1 more source

Exploring the Time to Intervene with a Reactive Mass Vaccination Campaign in Measles Epidemics. [PDF]

, 2006
The current WHO policy during measles outbreaks focuses on case management rather than reactive vaccination campaigns in urban areas of resource-poor countries having low vaccine coverage.
R. F. GRAIS, Grais, R, C. DUBRAY, Guerin, P J, Dubray, C, F. FERMON, X. DE RADIGUÈS, Fermon, F, Grais, RF, de Radiguès, X, Guerin, PJ, P. J. GUERIN   +11 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Vaccination against Foot-and-mouth disease : do initial conditions affect its benefit? [PDF]

, 2013
When facing incursion of a major livestock infectious disease, the decision to implement a vaccination programme is made at the national level. To make this decision, governments must consider whether the benefits of vaccination are sufficient to ...
Auty, Harriet K., Michael J. Tildesley (123224), Porphyre Thibaud, Tildesley Michael J., Auty, HK, Tildesley,, MJ, Harriet K. Auty (333828), George J. Gunn (467023), Woolhouse, Mark E. J., Porphyre, Thibaud, Auty Harriet K., Thibaud Porphyre (124835), Porphyre, T, Michael J Tildesley, Auty, Harriet K, Gunn, GJ, Woolhouse, Mark E J; id_orcid, Woolhouse Mark E. J., Mark E J Woolhouse, Gunn George J., Harriet K Auty, Woolhouse, MEJ, Woolhouse, M. E. J., (Mark E. J.), Tildesley, Michael J., Mark E. J. Woolhouse (163944), Colizza, Vittoria, Tildesley, Michael J, Thibaud Porphyre, George J Gunn, Gunn, George J., Gunn, George J   +30 more
core   +2 more sources

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Evaluation of cost-effective strategies for rabies post-exposure vaccination in low-income countries [PDF]

, 2011
<b>Background:</b> Prompt post-exposure prophylaxis (PEP) is essential in preventing the fatal onset of disease in persons exposed to rabies.
Hampson Katie, Katie Hampson, Briggs Deborah, Cleaveland, Sarah, Sarah Cleaveland, Briggs, Deborah, Deborah Briggs, Hampson, Katie, Cleaveland Sarah   +8 more
core   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source