Results 121 to 130 of about 16,461 (269)

Functional characterization of 42 CK2α de novo variants associated with Okur‐Chung neurodevelopmental syndrome

The FEBS Journal, EarlyView.
Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast, Christian Werner, Karsten Niefind, Joachim Jose   +3 more
wiley   +1 more source

Entre pierres et bétons, routes de montagne et transitions écologiques du tourisme, l’exemple du Vercors (1870-2023)

Mondes du Tourisme
This article examines the role of mountain roads in the ecological transition of the tourism sector. Based on a territorial research approach developed on the Vercors massif (France), this study examines the long-term links between tourism, roads, and ...
Emma-Sophie Mouret
doaj   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

The FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb, Dominik Hörtnagel, Chris Oostenbrink, Paul G. Furtmüller, Stefan Hofbauer   +4 more
wiley   +1 more source

Le paysage agro-pastoral villageois du Massif Central (The agro-pastoral village landscape in the Massif Central)

Bulletin de l'Association de géographes français, 1991
Résumé. - Recherche de signification d'un vieux paysage : minuscule « village » avec ses terres privées «ouvertes» et sa lande commune. Espace de pauvreté persistante, à l'écart des herbages pastoraux de la vraie montagne comme des terroirs entièrement cultivés des régions basses.
openaire   +2 more sources

Les bâtiments d'élevage dans le Massif Central

, 1988
This study has been given to the Cemagref in Clermont-Ferrand to define the current situation of animal houses in the North of the Central massif and to propose improvements.
Dobremez, Laurent, Lablanquie, M., Dutheil, B., Dobremez, L., Jaubourg, J.   +4 more
core   +2 more sources

Frequency of arboreality is correlated with longer hand skeletons in Gorilla: Analysis of a new skeletal sample of Bwindi mountain gorillas

Journal of Anatomy, EarlyView.
Variation in arboreality across gorilla populations is associated with systematic differences in manual digital lengths. Using a new dataset of linear metrics from the Bwindi mountain gorillas, we quantify metacarpal and phalangeal lengths in eastern and western gorilla populations across all five rays. Consistent with quantified behavioral differences,
Elliot G. Greiner, Christopher B. Ruff, Charlotte King, Aventino Nkwasibwe, Thadee Muhire, Emmanuel Tibenda, Jason S. Massey, Juho‐Antti Junno, Rowan M. Sherwood, Jean Bosco Noheri, Fred Nizeyimana, Tierra Smiley Evans, Richard Muvunyi, Dennis Babaasa, Martha M. Robbins, Shannon C. McFarlin, Tracy L. Kivell   +16 more
wiley   +1 more source

Short-lived active margin magmatism preceding Variscan collision in the Western French Massif Central

BSGF - Earth Sciences Bulletin
This paper presents and discusses new geochronological and petrological data on a suite of calc-alkaline plutons composed predominantly of diorites and tonalites from the West Massif Central.
Berger Julien, Beau-Hurdebourcq Léa, Serrano Julien, Benoit Mathieu, Grégoire Michel, Benmammar Anissa, Duchene Stéphanie, Bruguier Olivier, Baele Jean-Marc   +8 more
doaj   +1 more source

Paléosurfaces d'altération du Massif central

, 2018
Au sein du Massif central, une majeure partie du relief est caractérisée par des géomorphologies en forme de plaines et plateaux. L'altitude des plateaux est hétérogène, elle peut varier de la centaine de mètres à plus de 1000m. Ces surfaces correspondent à des surfaces d'aplanissement portant des profils d'altération.
Baptiste, Julien, Wyns, Robert
openaire   +1 more source

Les villes du Massif Central : P. Estienne, Villes du Massif Central Clermont-Ferrand

, 1964
Brunet-Le Rouzic Lucienne. Les villes du Massif Central : P. Estienne, Villes du Massif Central Clermont-Ferrand. In: Revue géographique des Pyrénées et du Sud-Ouest, tome 35, fascicule 2, 1964. pp.
Brunet-Le Rouzic, Lucienne
core  

Endocranial anatomy of the earliest Cretaceous European neosuchian crocodyliform Pholidosaurus purbeckensis provides new evidence for the ecological evolution of Pholidosauridae

Journal of Anatomy, EarlyView.
We present new insights into the internal cranial anatomy of the neosuchian crocodyliform Pholidosaurus purbeckensis, based on CT‐scan data of material from the lowermost Cretaceous Purbeck Limestone Group, southern UK. From the study of the endocast, we obtained new information on the phylogeny and the ecological evolution of the Family ...
Leonardo Barbini, Paul M. J. Burke, Ilaria Caddeo, Marco Romano, Philip D. Mannion   +4 more
wiley   +1 more source