Results 21 to 30 of about 11,784 (161)

Identification of common predisposing loci to hematopoietic cancers in four dog breeds.

open access: yesPLoS Genetics, 2021
Histiocytic sarcoma (HS) is a rare but aggressive cancer in both humans and dogs. The spontaneous canine model, which has clinical, epidemiological, and histological similarities with human HS and specific breed predispositions, provides a unique ...
Benoît Hédan   +10 more
doaj   +1 more source

Neoplastic lesions in domestic pigs detected at slaughter: literature review and a 20-year review (1998–2018) of carcass inspection in Catalonia

open access: yesPorcine Health Management, 2021
Background The present paper reviews the occurrence of neoplasms in swine and presents a case series of 56 tumors submitted to the Slaughterhouse Support Network (Servei de Suport a Escorxadors [SESC] IRTA-CReSA]) from slaughtered pigs from 1998 to 2018 (
Antonia Morey-Matamalas   +7 more
doaj   +1 more source

Analysis of the Prevalence of Canine Splenic Mass Lesions in Republic of Korea via Histopathological Diagnosis with Immunohistochemistry

open access: yesVeterinary Sciences, 2023
The histopathological diagnosis of canine splenic mass lesions is crucial for prognostication. However, thus far, no study has been conducted on the histopathology of canine splenic mass lesions in Republic of Korea.
Yeong-Ung Ko   +3 more
doaj   +1 more source

Changes in mast cell infiltration: a possible mechanism in detrusor overactivity induced by visceral hypersensitivity

open access: yesInternational Brazilian Journal of Urology, 2016
Objective: To establish the detrusor overactivity (DO) model induced by visceral hypersensitivity (VH) and investigate the relationship between mast cell (MC) infiltration and DO.
Nian-zhao Zhang   +4 more
doaj   +1 more source

Evaluation of plasma nucleosome concentrations in dogs with a variety of common cancers and in healthy dogs

open access: yesBMC Veterinary Research, 2022
Background Cell free DNA, in the form of nucleosomes, is released into circulation during apoptosis and necrosis in a variety of diseases. They are small fragments of chromosomes that are composed of DNA wrapped around a histone core made of four ...
H. M. Wilson-Robles   +8 more
doaj   +1 more source

High intensity focused ultrasound for the treatment of solid tumors: a pilot study in canine cancer patients

open access: yesInternational Journal of Hyperthermia, 2022
Purpose To investigate the safety, feasibility, and outcomes of High-Intensity Focused Ultrasound (HIFU) for the treatment of solid tumors in a spontaneous canine cancer model.Methods Dogs diagnosed with subcutaneous solid tumors were recruited, staged ...
Jennifer Carroll   +8 more
doaj   +1 more source

Ewing Sarcoma Developed at the Site of Previous Mast Cell Proliferation

open access: yesCureus, 2023
KIT gene mutations in Ewing sarcomas are rare; however, they are much more frequent in other neoplasms, namely mastocytosis. We describe a case of an adult male with a one-year duration of recurrent episodes of pain, swelling, and redness on the proximal phalanx of the third finger of his right hand.
Ranchor, Ridhi   +4 more
openaire   +2 more sources

Clinical validation of a next-generation sequencing-based multi-cancer early detection “liquid biopsy” blood test in over 1,000 dogs using an independent testing set: The CANcer Detection in Dogs (CANDiD) study

open access: yesPLoS ONE, 2022
Cancer is the leading cause of death in dogs, yet there are no established screening paradigms for early detection. Liquid biopsy methods that interrogate cancer-derived genomic alterations in cell-free DNA in blood are being adopted for multi-cancer ...
Andi Flory   +64 more
doaj   +2 more sources

The High Expression of Legumain in Canine Neoplasms: A Retrospective Analysis of 100 Cases

open access: yesAnimals, 2022
Legumain, a novel asparaginyl endopeptidase, has been observed to be overexpressed in several types of human solid tumors. Elevated levels of legumain are found in human cancers, and this oncoprotein may facilitate tumor invasion and metastasis when ...
Chiao-Hsu Ke   +5 more
doaj   +1 more source

A comprehensive multi-domain dataset for mitotic figure detection

open access: yesScientific Data, 2023
The prognostic value of mitotic figures in tumor tissue is well-established for many tumor types and automating this task is of high research interest.
Marc Aubreville   +11 more
doaj   +1 more source

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