Results 31 to 40 of about 11,784 (161)

Histomorphological and immunohistochemical characterization of 172 cutaneous round cell tumours in dogs

Pesquisa Veterinária Brasileira, 2012
This paper describes the use of a panel of antibodies (CD117, CD3, CD79a, CD45, cytokeratin, vimentin and E-cadherin) on formalin-fixed, paraffin-embedded sections of canine cutaneous round cell tumours. Neoplastic tumours were diagnosed by histology and
Marina Rios Araújo, Ingred Sales Preis, Gleidice Eunice Lavalle, Geovanni Dantas Cassali, Roselene Ecco   +4 more
doaj   +1 more source

Sentinel Lymph Node Biopsy Is Feasible in Dogs with Scars from Prior Local Excision of Solid Malignancies

Animals, 2022
Sentinel lymph node (SLN) biopsy is a well-established staging tool in canine oncology. This study aims to explore the feasibility of SLN biopsy in dogs with scars from prior excised solid malignancies that were referred for further tumor staging and/or ...
Elisa Maria Gariboldi, Damiano Stefanello, Mirja Christine Nolff, Donatella De Zani, Davide Zani, Valeria Grieco, Chiara Giudice, Camilla Recordati, Francesco Ferrari, Roberta Ferrari, Lavinia Elena Chiti   +10 more
doaj   +1 more source

Digital Lesions in Dogs: A Statistical Breed Analysis of 2912 Cases

Veterinary Sciences, 2021
Breed predispositions to canine digital neoplasms are well known. However, there is currently no statistical analysis identifying the least affected breeds. To this end, 2912 canine amputated digits submitted from 2014–2019 to the Laboklin GmbH & Co.
Julia Maria Grassinger, Andreas Floren, Tobias Müller, Argiñe Cerezo-Echevarria, Christoph Beitzinger, David Conrad, Katrin Törner, Marlies Staudacher, Heike Aupperle-Lellbach   +8 more
doaj   +1 more source

A review of neoplastic and non-neoplastic canine skin tumours in Trinidad from 2010-2015

Brazilian Journal of Veterinary Pathology, 2019
This retrospective study was performed on samples submitted to the Pathology Unit of the School of Veterinary Medicine, Faculty of Medical Sciences, St. Augustine, Trinidad, during the period 2010 to 2015. A total of 471 non-inflammatory cutaneous masses
Rod Suepaul, Stacy Rajh, Karelma Frontera-Acevedo, Indira Pargass, Sharianne Suepaul   +4 more
doaj   +1 more source

DPP6 and MFAP5 are associated with immune infiltration as diagnostic biomarkers in distinguishing uterine leiomyosarcoma from leiomyoma

Frontiers in Oncology, 2022
ObjectiveUterine leiomyosarcoma (ULMS) is the most common subtype of uterine sarcoma and is difficult to discern from uterine leiomyoma (ULM) preoperatively.
Yumin Ke, LiuXia You, YanJuan Xu, Dandan Wu, Qiuya Lin, Zhuna Wu   +5 more
doaj   +1 more source

Acute phase protein levels in dogs with mast cell tumours and sarcomas [PDF]

Veterinary Record, 2012
The acute phase proteins (APP) form part of a non‐specific host response to inflammation. They may be induced by a range of different causes, including infection, inflammation, cancer and trauma. As they form part of the earliest response to such insults, they have potential for early identification of disease.
Chase, D., McLauchlan, G., Eckersall, P., Pratschke, J., Parkin, T., Pratschke, K.   +5 more
openaire   +4 more sources

3114 Investigating the therapeutic potential of parthenolide in the treatment of hematopoietic neoplasms in dogs

Journal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: Determine PTL’s mechanism(s) of action in a panel of canine hematopoietic cell lines; this will enable us to 1) verify that PTL is working as expected and 2) rationally select combination therapeutics.
Lisa J Schlein, Aubree Peterson, Barbara Rose, Douglas Thamm   +3 more
doaj   +1 more source

Modulation of Peripheral Mast Cell and Brain Microglia Axis via Kinase Inhibition

Metabolites
Background/Objectives: Kinase inhibition is a hot therapeutic strategy for several human diseases, including neurodegeneration. Tyrosine kinase c-KIT activates peripheral mast cells, while other kinases including Abelson (c-Abl) promotes autophagy and ...
Xiaoguang Liu, Michaeline Hebron, Kaluvu Balaraman, Louis Ballard, Kimberly Liu, Max Stevenson, Charbel Moussa   +6 more
doaj   +1 more source

Ferroptosis-related gene HIC1 in the prediction of the prognosis and immunotherapeutic efficacy with immunological activity

Frontiers in Immunology, 2023
BackgroundHypermethylated in Cancer 1 (HIC1) was originally confirmed as a tumor suppressor and has been found to be hypermethylated in human cancers. Although growing evidence has supported the critical roles of HIC1 in cancer initiation and development,
Yanlin Wu, Zhengjun Lin, Xianzhe Tang, Zhongyi Tong, Yuqiao Ji, Yingting Xu, Ziting Zhou, Jing Yang, Zhihong Li, Tang Liu   +9 more
doaj   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source