Results 351 to 360 of about 10,756,993 (383)
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Identification of Mast Cells and Mast Cell Subpopulations
2008Mast cells generate mediators of inflammation which are stored in granules and secreted on activation either by allergen crosslinking of membrane-bound IgE or through other stimuli. Most methods for mast cell identification rely on the histochemical detection of constituents of the secretory granules. Although staining for mast cells with histochemical
Buckley, Mark, Walls, Andrew F.
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Thrombosis and Haemostasis, 2011
SummaryThe mast cell, a potent inflammatory cell type, is widely distributed over several tissues, but particularly prominent at the interface exposed to the environment to act in the first line of defense against pathogens. Upon activation mast cells release granules, which contain a large panel of mediators, including neutral proteases (e.g.
Erik A.L. Biessen, Ilze Bot
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SummaryThe mast cell, a potent inflammatory cell type, is widely distributed over several tissues, but particularly prominent at the interface exposed to the environment to act in the first line of defense against pathogens. Upon activation mast cells release granules, which contain a large panel of mediators, including neutral proteases (e.g.
Erik A.L. Biessen, Ilze Bot
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Human mast cell proteases and mast cell heterogeneity
Current Opinion in Immunology, 1988Mast cell neutral proteases are distinctive markers of the MC(T) and MC(TC) cells in humans. Measurements of tryptase levels in vivo serve as an overall indicator of mast cell activity. Further research is needed to evaluate the functional role of these proteases as well as each mast cell type in situations related to both health and disease.
J.S. Miller, Lawrence B. Schwartz
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, 2011 The controversial, and for long elusive, story of MCs begins on a remote day in the summer 1878, precisely on the 17th June of that year, when a 24-year-old medical student, the future Nobel Prize laureate Paul Ehrlich, discussed his doctoral thesis at the Medical Faculty of Leipzig University (Fig. 2.1).
Enrico Crivellato, Domenico Ribatti
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Giornale Italiano di Dermatologia e Venereologia, 2019
Mast cells (MCs) are a potent proangiogenic factor in tumors, they product several pro-angiogenic factors such as fibroblast growth factor 2 (FGF-2), vascular epithelial growth factor (VEGF), tryptase and chymase. Tryptase is a serine protease classified as α-tryptase and β-tryptase, both produced by MCs.
Stefano Calvieri +8 more
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Mast cells (MCs) are a potent proangiogenic factor in tumors, they product several pro-angiogenic factors such as fibroblast growth factor 2 (FGF-2), vascular epithelial growth factor (VEGF), tryptase and chymase. Tryptase is a serine protease classified as α-tryptase and β-tryptase, both produced by MCs.
Stefano Calvieri +8 more
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Joint Bone Spine, 2013
The prominent role for mast cells in the inflammatory response has been increasingly well documented in recent years. Mast cells not only contribute to maintain homeostasis via degranulation and to generate IgE-mediated allergic reactions, but also sit at a major crossroads for both innate and adaptive immune responses. The part played by mast cells in
Olivier Hermine, Laurent Frenzel
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The prominent role for mast cells in the inflammatory response has been increasingly well documented in recent years. Mast cells not only contribute to maintain homeostasis via degranulation and to generate IgE-mediated allergic reactions, but also sit at a major crossroads for both innate and adaptive immune responses. The part played by mast cells in
Olivier Hermine, Laurent Frenzel
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Mast Cell Pleomorphism: Properties of Intestinal Mast Cells
1987Consistent with their nearly ubiquitous distribution throughout the body, mast cells interact with a variety of cell types and react to numerous environmental stimuli. They can be activated by macrophage (1) and T cell factors (2), by complement fragments, as well as by IgE-allergen interactions.
R. H. Stead +4 more
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Immunological Reviews, 2018
SummaryMast cells are a part of the innate immune system implicated in allergic reactions and the regulation of host‐pathogen interactions. The distribution, morphology and biochemical composition of mast cells has been studied in detail in vitro and on tissue sections both at the light microscopic and ultrastructural level.
Sabine Buhner +10 more
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SummaryMast cells are a part of the innate immune system implicated in allergic reactions and the regulation of host‐pathogen interactions. The distribution, morphology and biochemical composition of mast cells has been studied in detail in vitro and on tissue sections both at the light microscopic and ultrastructural level.
Sabine Buhner +10 more
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Plastic and Reconstructive Surgery, 2004
Hemangioma is a primary tumor of the microvasculature in which angiogenesis is initially excessive, followed by spontaneous regression of the newly formed vessels, with the cellular parenchyma gradually being replaced with fibrofatty tissue. Mast cells, which are highly heterogenous in terms of their morphology, function, and metabolic products, have ...
Swee T. Tan +3 more
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Hemangioma is a primary tumor of the microvasculature in which angiogenesis is initially excessive, followed by spontaneous regression of the newly formed vessels, with the cellular parenchyma gradually being replaced with fibrofatty tissue. Mast cells, which are highly heterogenous in terms of their morphology, function, and metabolic products, have ...
Swee T. Tan +3 more
openaire +3 more sources