Results 361 to 370 of about 10,756,993 (383)
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British Medical Bulletin, 1992
The mast cell's association with asthma has a long history dating back to the turn of the century, when Dale and Laidlaw described histamine as a spasmogen for guinea-pig airways and a proposed mediator of acute anaphylaxis. Almost half a century elapsed before histamine was localised to the granules of mast cells, although the release of this and ...
M K Church, S. T. Holgate
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The mast cell's association with asthma has a long history dating back to the turn of the century, when Dale and Laidlaw described histamine as a spasmogen for guinea-pig airways and a proposed mediator of acute anaphylaxis. Almost half a century elapsed before histamine was localised to the granules of mast cells, although the release of this and ...
M K Church, S. T. Holgate
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Current Allergy and Asthma Reports, 2016
For half a century, it has been known that the mast cell is the cell responsible for the majority of anaphylactic events. Its mediators, taken as a whole, are capable of producing all of the clinical manifestations of these events. With the discovery of immunoglobulin E (IgE), it was originally felt that the vast majority of anaphylactic episodes were ...
Lene Heise Garvey, Phil Lieberman
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For half a century, it has been known that the mast cell is the cell responsible for the majority of anaphylactic events. Its mediators, taken as a whole, are capable of producing all of the clinical manifestations of these events. With the discovery of immunoglobulin E (IgE), it was originally felt that the vast majority of anaphylactic episodes were ...
Lene Heise Garvey, Phil Lieberman
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Journal of biological regulators and homeostatic agents, 2009
Mast cells play a role in various physiological functions: innate and acquired immunity, epithelium remodelling and proliferation, angiogenesis, cancer, inflammation and infections. Mast cells are activated by cross-linking of FcERI molecules, which are involved in the binding of multivalent antigens to the attached IgE molecules, resulting in a ...
FELACO, PAOLO+19 more
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Mast cells play a role in various physiological functions: innate and acquired immunity, epithelium remodelling and proliferation, angiogenesis, cancer, inflammation and infections. Mast cells are activated by cross-linking of FcERI molecules, which are involved in the binding of multivalent antigens to the attached IgE molecules, resulting in a ...
FELACO, PAOLO+19 more
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Mast cells and mast cell neoplasia: a review*
Histopathology, 1979M. R. Parwaresch, Karl Lennert
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Science, 1966
Subcutaneous injections of normally well tolerated amounts of hypertonic NaCl or urea solutions produce extensive topical necroses in rats systemically treated with various mast-cell dischargers and mast-cell products. This response is considered to be closely related to mast-cell function, for it cannot be duplicated by systemic treatment with a ...
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Subcutaneous injections of normally well tolerated amounts of hypertonic NaCl or urea solutions produce extensive topical necroses in rats systemically treated with various mast-cell dischargers and mast-cell products. This response is considered to be closely related to mast-cell function, for it cannot be duplicated by systemic treatment with a ...
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[42] Mast cells and mast cell products
1988Publisher Summary This chapter discusses the techniques utilized for isolating and purifying mast cells from tissues and animals in which the inflammatory process is being studied. Methods used for measuring some of the chemical mediators contained in mast-cell granules and shown to have importance in inflammation and many methods for assessing the ...
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Molecular Immunology, 1982
Mast cells secrete histamine, glycosaminoglycans, arachidonic acid derivatives, enzymes, and possibly whole granules. Physiologic stimuli include the bridging of membrane-bound IgE molecules by antigen, the anaphylatoxins C5a and C3a, and the neurotransmitter acetylcholine.
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Mast cells secrete histamine, glycosaminoglycans, arachidonic acid derivatives, enzymes, and possibly whole granules. Physiologic stimuli include the bridging of membrane-bound IgE molecules by antigen, the anaphylatoxins C5a and C3a, and the neurotransmitter acetylcholine.
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Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases
Nature reviews. Immunology, 2021P. Kolkhir+4 more
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