Results 101 to 110 of about 148,300 (268)

Mast Cell Frequency in Oral Squamous Cell Carcinoma [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Oral squamous cell carcinoma is the most common malignancy of the oral cavity. In solid tumors, cancer cells and stromal cells (fibroblasts, inflammatory cells, endothelial cells) play a role in tumor progression, angiogenesis ...
Najmeh Jafari, Seyed Mostafa Mahmoudi, Fatemeh Taherneghad   +2 more
doaj  

Correlation of intratumoral mast cell quantity with psychosocial distress in patients with pancreatic cancer: the PancStress study

Scientific Reports
Mast cells are commonly found in pancreatic ductal adenocarcinoma (PDAC), yet their role in the disease remains uncertain. Although mast cells have been associated with depression in several diseases, their connection to PDAC in this context remains ...
Alicia Sitte, Ruediger Goess, Tutku Tüfekçi, Ilaria Pergolini, Paulo Leonardo Pfitzinger, Eloísa Salvo-Romero, Carmen Mota Reyes, Sergey Tokalov, Okan Safak, Hendrik Steenfadt, Ibrahim H. Gürcinar, Ümmügülsüm Yurteri, Miriam Goebel-Stengel, Gemma Mazzuoli-Weber, Andreas Stengel, Mert Erkan, Helmut Friess, Rouzanna Istvanffy, Güralp Onur Ceyhan, Elke Demir, Ihsan Ekin Demir   +20 more
doaj   +1 more source

The Mast Cell [PDF]

Journal of the Royal Society of Medicine, 1980
openaire   +2 more sources

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

On the Role of Mast Cells and Their Proteases in the Severe COVID-19

Архивъ внутренней медицины
During the pandemic of the new coronavirus infection COVID-19 the question about the importance of mast cells and their proteases arose.   The aim of this study is to determine the role of mast cells and their proteases chymase and tryptase in the ...
A. V. Budnevsky, S. N. Avdeev, E. S. Ovsyannikov, I. A. Savushkina, O. N. Choporov, V. V. Shishkina, A. V. Pertsev, I. M. Perveeva, N. G. Alekseeva   +8 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Evidence for adaptive explanations of semelparity in animals

Biological Reviews, EarlyView.
ABSTRACT Semelparity, the reproductive strategy of reproducing once, is widespread but uncommon in animals. Classes of models to explain the evolution of semelparity are based either on age structure and mortality schedules – demographic models in which high post‐reproductive mortality risk favours high reproductive effort and semelparity results from ...
Diana O. Fisher, Roberto Salguero‐Gómez   +1 more
wiley   +1 more source