Results 171 to 180 of about 294,471 (310)

Gut-Brain Inflammation and Disrupted Homeostasis Due to Activation of Mast Cells and Microglia. [PDF]

Int J Mol Sci
Katiraei P, Frye RE, Theoharides TC.
europepmc   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Atypical mast cells and multiple myeloma: An ambiguous alliance with diagnostic implications. [PDF]

Br J Haematol
Rieu JB, Schavgoulidze A, Canali A, Largeaud L, Perrot A, Syrykh C.   +5 more
europepmc   +1 more source

Prevalence of disorders of gut–brain‐interaction in pediatric patients with in‐remission inflammatory bowel disease: An Italian multicenter study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric patients with in‐remission inflammatory bowel disease (IBD) often report persistent gastrointestinal symptoms, suggesting a potential overlap with disorders of gut–brain‐interaction (DGBIs). While DGBIs affect up to 40% of the general population, their prevalence in quiescent IBD children remains limited.
Giovanna Quatrale, Niccolo’ Chirico, Luigi Colecchia, Giuseppe Stella, Francesco Proli, Pietro Pisano, Erminia Romeo, Paola De Angelis, Licia Pensabene, Giovanni Marasco, Giovanni Di Nardo, Giovanni Barbara, Antonio Gasbarrini, Franco Scaldaferri, Valentina Giorgio   +14 more
wiley   +1 more source

Antibiotics in the first week of life are not associated with functional gastrointestinal disorders at 9–12 years of age

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Dysbiosis due to early‐life antibiotics may contribute to the development of functional gastrointestinal disorders (FGIDs). This follow‐up study of a birth cohort primarily investigates the association between antibiotic treatment in the first week of life and the presence of FGIDs at 9–12 years.
Nora C. Carpay, Kim Kamphorst, Ruurd M. van Elburg, Arine M. Vlieger   +3 more
wiley   +1 more source

Deciphering the Role of Mast Cells in HPV-Related Cancers. [PDF]

Int J Mol Sci
Espinosa-Riquer ZP, Muñoz-Bello JO, González-Espinosa C, Ibarra-Sánchez A, Lizano M.   +4 more
europepmc   +1 more source

Phytochemical content, antioxidant and antibacterial properties of Typhonium flagelliforme cultivated via soil and hydroponic methods

JSFA reports, EarlyView.
Abstract Background Typhonium flagelliforme is a medicinal herb in the Araceae family, widely distributed in Southeast Asia. This study aimed to evaluate the effects of hydroponic and soil‐based cultivation systems on the phytochemical content and bioactivity of T. flagelliforme. Results Using liquid chromatography‐mass spectrometry (LC‐MS) analysis, 9
Yen Ning Lee, Norsharina Md Saad, Siti Rokhiyah Ahmad Usuldin, Seetha Jaganathan King, Wee Sim Choo   +4 more
wiley   +1 more source

Serous Cavity Mast Cells Depend on the ROQUIN Paralogs. [PDF]

Eur J Immunol
Heger K, Masjedi A, Yeroslaviz A, Zeng T, Baygün S, Vicente-Luque A, Lien CI, Osswald L, Saur D, Kovacs D, Schmidt-Supprian M.   +10 more
europepmc   +1 more source

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza, Hyeonjun Yu, Jonghyun Jeong, Jung Cheul Shin, Woo Jung Kim, Sung‐Kwon Moon, Hoon Kim   +6 more
wiley   +1 more source