Results 171 to 180 of about 148,300 (268)

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

open access: yesPhytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan   +8 more
wiley   +1 more source

PAC regulates endo-, and exocytosis, and lysosomal-mitochondrial stress signaling in human mast cells. [PDF]

open access: yesCell Commun Signal
Melek K   +8 more
europepmc   +1 more source

The evaluation of boundary‐layer turbulence in high‐resolution numerical weather prediction simulations using Doppler lidar

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
A new method compares both kilometer and sub‐kilometre weather model simulations with Doppler lidar observations to assess the representation of boundary‐layer turbulence. While bulk boundary‐layer properties are well represented, vertical velocity variance is strongly underestimated in both simulations.
Natalie J. Harvey   +7 more
wiley   +1 more source

Impact of sleep insufficiency and recovery on cancer development

open access: yesSleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

Deepening the real options debate: Real options as dynamic optimization

open access: yesStrategic Management Journal, EarlyView.
Abstract Research Summary Is real option theory useful for management research? This topic was hotly debated two decades ago. Real options were said to be inapplicable to management research and to lack conceptual distinctiveness. Whereas responses to the claim about the non‐distinctiveness of real options were disparate, the concern about the theory's
Arkadiy V. Sakhartov   +2 more
wiley   +1 more source

Mast cells shape early pulmonary inflammation and regulate dendritic cell abundance and localization after chemical induced lung injury. [PDF]

open access: yesFront Immunol
Gibb M   +8 more
europepmc   +1 more source

Exploring the potential of Textile Reinforced Concrete for corrosion‐insensitive retaining walls

open access: yesStructural Concrete, EarlyView.
Abstract In a context where durability concerns, particularly the corrosion of steel reinforcement, remain a critical challenge for conventional reinforced concrete structures under severe exposure, Textile Reinforced Concrete (TRC) is emerging as a promising alternative.
J. Devènes   +3 more
wiley   +1 more source

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