Results 101 to 110 of about 1,966,371 (280)
THE WORST ARGUMENT IN THE WORLD – DEFENDED
In this article, I argue that Berkeley's master argument is not the worst argument in the world – more like third or fourth.
Scott Stapleford
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A ‘companions in guilt’ (CG) strategy against moral error theory aims to show that the latter proves too much: if sound, it supports an implausible error-theoretic conclusion in other areas such as epistemic or practical reasoning.
Ramon Das (8509131)
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Study in Arthur's thesis about Marx's Being influenced by Hegel's Master-Servant in Labor
o one is denying that Hegel had a strong influence on Marx, especially influenced by the Master-Servitude of Phenomenology of Spirit. For people like Arthur, however, it is not more than a Myth.
Mojtaba Seifi , Mohammad Meshkat
doaj
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Flavio Baroncelli: A Personal Recollection
Flavio Baroncelli was a formidable philosopher, albeit an unusual—and even "disquieting"—one. His work is well known in Italy, but little known in other countries.
Mikael M. Karlsson
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
On Philosophers' Hallucinations: Naïve Realism and the Master Argument from Hallucination [PDF]
It is widely acknowledged that the Master Argument from Hallucination poses a significant challenge to Naïve Realism, i.e., the view that the phenomenal character of (at least) veridical conscious perceptions is constituted by the obtaining of a relation
Mazzullo, Giorgio
core

