Results 81 to 90 of about 2,428,488 (282)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Against trauma: silence, victimhood, and (photo-)voice in northern Namibia

open access: yesActa Academica, 2015
The article shows how the discourses of trauma, victimhood and silence regarding local agency contributed to the production of the nationalist master narrative in postcolonial Namibia. However, I point out repositories of memory beyond the narratives of
Heike Becker
doaj   +3 more sources

An atheological argument from evil : a thesis presented in partial fulfillment of the requirements for the degree of Master of Arts in Philosophy at Massey University [PDF]

open access: yes, 1990
Ever since ancient times it has occurred to many people, great and small, that the existence of evil constitutes evidence against that of God. The central claim of this thesis is that, contrary to theistic belief, this evidence is decisive.
Bako, Charles Karoly
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Comment le scepticisme est devenu un système. La classification de Jules Vuillemin et ses transformations

open access: yesPhilosophia Scientiæ, 2016
In an unpublished text dated 1979, Jules Vuillemin sent the Finnish philosopher and logician Georg Henrik von Wright a list of solutions to the Master Argument.
Baptiste Mélès
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Islamism Revisited: A Lacanian Discourse Critique [PDF]

open access: yes, 2014
The aim of this article is to highlight the relevance of Lacanian psychoanaly-sis for an understanding of Islamism, unfolding its discursive-ideological complexity.
Mura, Andrea
core  

Different Clusters of Text from Ancient China, Different Mathematical Ontologies

open access: yes, 2019
Sources attesting to mathematical activities in ancient China form at least four distinct clusters of texts, bespeaking at least four different—though overlapping—ways of practicing mathematics. I will focus on two such sets of documents: the canons that
Chemla, K.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

UNE PROCÉDURE EN DIFFICULTÉ: A BLUEPRINT FOR RESOLVING “SPECIAL” EDUCATION DISPUTES THROUGH A QUASI-INQUISITORIAL ADMINISTRATIVE PROCESS

open access: yesThe Windsor Yearbook of Access to Justice, 2015
In this essay, disability practitioner and scholar Stephen Rosenbaum proposes a radical change in the United States administrative adversarial adjudicatory process for resolution of “special” education disputes between educators and students with ...
Stephen A Rosenbaum
doaj   +1 more source

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