Results 41 to 50 of about 2,814,225 (308)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Programa de Pós-Graduação em Geologia - Dissertações Defendidas 1998 - Mestrado - Instituto de Geociências - Universidade Federal do Rio de Janeiro [PDF]

open access: yesAnuário do Instituto de Geociências, 1998
106 Programa de Pós-Graduação em Geologia Dissertações Defendidas - Mestrado Nome: Cristiane Mendes Coelho Título: Análise Técnica-Econômica-Financeira de Projetos em Rochas Ornamentais no Município do Rio de Janeiro e Região Metropolitana - Estudos
doaj  

A New Face at the Reference Desk [PDF]

open access: yes, 2013
Hi there! I’m Sarah and I’m a graduate reference intern this fall at the Musselman Library. I’m currently in my last semester of completing my Master of Library Science degree with Clarion University of Pennsylvania.
Myers, Sarah
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Students and Teachers’ View about Educational Regulation Related to Continuing Education without Entrance Exam [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2012
Introduction: In recent years, ministry of health and medical education has approved a regulation for accepting top students for postgraduate courses without entrance exam that leads to many critiques and discussions. This article addressed students’ and
Mahsa Shakour   +2 more
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Challenges and Solutions of MSc Education in Nursing: A Qualitative Study [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2012
Introduction: Alteration and adjustment of nursing care system in 21st century depends on its success in designing the nursing pedagogical models. This study was conducted in order to identify and explain the challenges in postgraduate (MSc) levels in ...
leila valizadeh   +3 more
doaj  

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