Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Programa de Pós-Graduação em Geografia - Dissertações Defendidas 1998 - Mestrado - Instituto de Geociências - Universidade Federal do Rio de Janeiro [PDF]
Anuário do Instituto de Geociências, 1998 96 Anuário do Instituto de Geociências - UFRJ Volume 21 / 1998 Programa de Pós-Graduação em Geografia Dissertações Defendidas - Mestrado Nome: Ana Lucia Vieira de Azevedo Título: Informação Geográfica e Imprensa: O Caso do Desenvolvimento ...
doaj
Challenges and Solutions of MSc Education in Nursing: A Qualitative Study [PDF]
مجله ایرانی آموزش در علوم پزشکی, 2012 Introduction: Alteration and adjustment of nursing care system in 21st century depends on its success in designing the nursing pedagogical models. This study was conducted in order to identify and explain the challenges in postgraduate (MSc) levels in ...
leila valizadeh +3 more
doaj
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Proposing Appropriate National Standards for Nursing and Midwifery Education Derived from International Standards: a Case Study, Master of Science in Nursing and Midwifery [PDF]
مجله ایرانی آموزش در علوم پزشکی, 2008 Introduction: Applying foreign standards for accreditation of Master of Science in nursing and midwifery in Iran seems anomalous. Taking advantage of these foreign standards as well as the views of experts in nursing and midwifery, the researcher in this
Maryam Allahdadian +3 more
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Journal of Evidence Based Health Policy, Management & Economics, 2022 Background: The main purpose of a health system is to provide quality care services, and providing orderly, high-quality, safe, and economic services requires skillful and knowledgeable nurses. Critical Care M.Sc.
Hamideh Ebrahimi +2 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A Research on the System of Master Education in Archival Science in Mainland China
Tūzī yǔ dàng’àn xuékān, 2016 A relatively complete system of master education in archival science in mainland China has been achieved after more than three decades of development. Through surveys on and content analysis of websites, websites of current 29 departments which recruit ...
Yan Zhang, Mei-Ling Wang
doaj +1 more source
Master of Science in Medical Statistics Programme at Universiti Sains Malaysia: 20 Years Ongoing. [PDF]
Malays J Med Sci, 2023 Norsa'adah B +6 more
europepmc +1 more source