Results 111 to 120 of about 308,319 (306)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Problem-Based Learning on Climate Change Theme: Concept Mastery Profile and Problem Solving Skills of Secondary Students [PDF]

, 2020
Bibin Rubini, Lita Juwita, Siti Aisyah
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

THE EFFECT OF PROJECT-BASED COLLABORATIVE LEARNING ON CONCEPT MASTERY OF MUSHROOM: THE CASE OF SENIOR HIGH SCHOOL STUDENTS IN INDONESIA

, 2020
Fatma Sukmawati, Punaji Setyosarı, Sulton Sulton, Purnomo Purnomo   +3 more
openalex   +1 more source

PENERAPAN LEARNING CYCLE UNTUK MENINGKATKAN PENGUASAAN KONSEP DAN PERUBAHAN KONSEPTUAL SISWA SMA PADA KONSEP SISTEM KOORDINASI [PDF]

, 2015
Penelitian ini dilatarbelakangi oleh permasalahan masih rendahnya penguasaan konsep dan perubahan konseptual siswa dalam pembelajaran. Tujuan penelitian ini untuk mengkaji peningkatan penguasaan konsep dan perubahan konseptual siswa yang mendapatkan ...
Maftuhah, -
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Concept Mastery of Physical Education Students In Multiple Representation (MR) Based Three Dimensional Solid Object Motion Mechanics (3DSOM)

, 2020
Tri Isti Hartini, S Liliasari, Syamsul Bahri Agus, Taufik Ramlan Ramalis   +3 more
openalex   +1 more source

IMPLEMENTASI PEMBELAJARAN IPA TERPADU MENGGUNAKAN PENDEKATAN SCIENCE WRITING HEURISTIC (SWH) UNTUK MENINGKATKAN PENGUASAAN KONSEP DAN KEMAMPUAN BERKOMUNIKASI SISWA SMP [PDF]

, 2015
Penelitian ini bertujuan untuk melihat peningkatan pembelajaran IPA terpadu menggunakan pendekatan SWH (Science Writing Heuristic) terhadap peningkatan penguasaan konsep dan kemampuan berkomunikasi siswa kelas VIII yang dilakukan di SMPN Sumatera Barat ...
Yusefni, Winda
core  

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Designing The Scientific Characteristics of Learning Model to Improve The Mastery of Concept on Nutrition Science II of Prospective Teachers of Physical and Health Education [PDF]

, 2018
Hartati Hartati, Herri Yusfi, Destriani
openalex   +1 more source