Results 81 to 90 of about 17,537 (259)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Inquiry Based Learning Model Natural Phenomena to Improve The Curiousity and Mastery of Teh Concept of Junior High School Student

EduHumaniora: Jurnal Pendidikan Dasar, 2016
The purpose of this study was to analyze the increase curiousity and mastery of the concept of junior high school students after participating in inquiry learning based on the natural phenomenon of motion plant material.
Soleh Hadiryanto, Dina Thaib
doaj   +1 more source

Interactive Multimedia Effectiveness in Improving Cell Concept Mastery

Journal of Biology Education, 2019
The learning process has been carried out in the conventional way, this is caused by the teacher's understanding of using multimedia is still not optimal, so the learning method used is still limited. This phenomenon makes the researchers interested in doing this research.
Saiman Rosamsi, Mieke Miarsyah, Rizhal Hendi Ristanto   +2 more
openaire   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Perbedaan metode debat dan ceramah terhadap penguasaan konsep IPS ditinjau dari berpikir kritis siswa

Harmoni Sosial: Jurnal Pendidikan IPS, 2018
Penelitian ini bertujuan untuk mengetahui perbedaan yang signifikan: (1) penguasaan konsep IPS yang dihasilkan oleh metode debat dan metode ceramah; (2) penguasaan konsep pada kemampuan berpikir kritis tinggi antara metode debat dan metode ceramah; (3 ...
Immawati Nur Aisyah Rivai, Taat Wulandari   +1 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Model Problem Based Learning Berbantuan Simulasi Komputer Untuk Meningkatkan Penguasaan Konsep Pada Materi Alat-Alat Optik

JPFT (Jurnal Pendidikan Fisika dan Teknologi), 2018
This research aims to determine the increase in mastery of  concept through  problem based learning model assisted by computer simulations on the material of class XI optical devices in SMAN 8 Mataram.
Khairun Niami, Kosim Kosim, Gunawan Gunawan   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Mastery Motivation, Mastery Pleasure, and Self-Concept in Singing of Students in Specialized and Non-Specialized Music Classes [PDF]

Education Sciences
This study aimed to investigate differences in mastery motivation (MM), mastery pleasure (MP), and self-concept (SC) in singing based on class type (specialized non-specialized music classes) and gender across four grades: 1, 3, 5, and 7. It also explored the relationships between students’ demographic variables and the fundamental motivational factors
Katalin Kovács, Márta Janurik, Tun Zaw Oo, Norbert Szabó, Krisztián Józsa   +4 more
openaire   +3 more sources