Results 111 to 120 of about 81,928 (305)
Equine Veterinary Education, EarlyView.Summary Background Endoscopy, including tracheal mucus score (TMS) and bronchoalveolar lavage (BAL) fluid cytology, is commonly employed in the diagnosis of equine asthma (EA). Large‐scale studies comparing clinical signs, TMS and BAL cytology are warranted.
M. Larsen +5 more
wiley +1 more source
Cutaneous mastocytosis: Clinical Case
Педиатрическая фармакологияSkin syndrome is common in the practice of allergologist-immunologist, and it requires differential diagnosis. One of the rare skin diseases among children is mastocytosis caused by excessive accumulation of mast cells in various organs.
Aset Kh. Ibisheva +5 more
doaj +1 more source
Gastric biopsies with prominent eosinophils: Clinicopathologic features and response to therapy
Histopathology, EarlyView.The use of the term ‘histologic eosinophilic gastritis’ (EoG) has been proposed for cases with ≥30 eosinophils/high power field (HPF) in five separate HPF and with no known associated causes of eosinophilia; however, these criteria can miss cases with clinically significant eosinophilia and our study results argue against using this term for pathology ...
Nigar Anjuman Khurram +2 more
wiley +1 more source
Diagnosing Systemic Mastocytosis: State of the Art
International Journal of Laboratory Hematology, EarlyView.ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley +1 more source
Journal of Immunology Research, 2019 Background. Mastocytosis is a condition characterized by the expansion and accumulation of mast cells (MCs) in various organs. The symptoms are related to the increased release of MC-derived mediators that exert local and distant effects.
Anne Lise Ferrara +9 more
doaj +1 more source
Immunology, EarlyView.(A) Proposed model for Abl1 degradation via Nbeal2. Nbeal2 interacts with Abl1 with its WDR domain. This results in proteasomal degradation by a yet unidentified ubiquitin ligase. Therefore, Nbeal2 inactivation stabilises Abl1, which supports mast cell (MC) degeneration. (B) In wt MCs, the Abl1 protein level is controlled by Nbeal2. Furthermore, Nbeal2
Raphaela Marquardt +10 more
wiley +1 more source
Childhood Pseudoxanthomatousmastocytosis; Report of two cases
Indian Journal of Dermatopathology and Diagnostic Dermatology, 2018 Cutaneous mastocytosis (CM) is a mast cell proliferative disorder that commonly affects pediatric population. It has various clinical forms such as urticaria pigmentosa, solitary mastocytoma, telangiectasia macularis eruptiva perstans, diffuse CM, and ...
Bhabani S. T. P. Singh +3 more
doaj +1 more source
Dermatoscopic findings of urticaria pigmentosa [PDF]
Anais Brasileiros de Dermatologia, 2013 Mastocytosis is a rare disease characterized by proliferation and accumulation of mast cells in various organs. The maculopapular cutaneus mastocytosis is divided into three subtypes: papular/plaque variant, urticaria pigmentosa and eruptive macular ...
Marcela Duarte Benez Miller +4 more
doaj +1 more source
Omalizumab for Pediatric Cutaneous Mastocytosis: Case Report and Review
Pediatric Dermatology, EarlyView.ABSTRACT We report an 11‐month‐old boy with diffuse cutaneous mastocytosis whose severe pruritus and steroid dependence resolved following off‐label treatment with omalizumab. A literature review identified five additional pediatric cases in which omalizumab led to complete symptom resolution in an average of 2 months and permitted discontinuation of ...
Janis Chang +3 more
wiley +1 more source