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Challenges in the Diagnosis of Cutaneous Mastocytosis
DiagnosticsBackground: Mastocytosis is characterized by an accumulation of clonal mast cells (MCs) in tissues such as the skin. Skin lesions in mastocytosis may be clinically subtle or heterogeneous, and giving the correct diagnosis can be difficult.
Knut Brockow +9 more
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, 2013 Mastocytosis is a mast cell disorder in which its exaggerated proliferation can occur in two forms: systemic and cutaneous (Davis et al., 1992). Because canine mastocytosis is a rare situation of controversial and difficult diagnosis, the goal of this ...
Mendonça, A., Paiva, D., Vala, Helena
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Allergen-specific immunotherapy of Hymenoptera venom allergy:also a matter of diagnosis [PDF]
, 2015 Stings of hymenoptera can induce IgE-mediated hypersensitivity reactions in venom-allergic patients, ranging from local up to severe systemic reactions and even fatal anaphylaxis.
Schiener, Maximilian +4 more
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Diffuse large B cell lymphoma coexistence with systemic mastocytosis
Journal of Cancer Research and Practice, 2016 Systemic mastocytosis is a rare disease and characterized by excessive mast cell accumulation in one or multiple organs. One subtype of systemic mastocytosis is systemic mastocytosis-associated clonal hematological non-mast cell lineage disease (SM-AHMND)
Sheng-Hsuan Chien +8 more
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Rare Clinical Image of Cutaneous Mastocytosis
Journal of Clinical and Diagnostic ResearchMastocytosis, a rare condition also referred to as a clonal bone marrow disorder, is characterised by an excessive presence of CD34+ mast cell progenitors and functionally impaired mast cells. This disorder can affect both adults and children, leading to
Shubham Khanke +3 more
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Mast cell leukemia with prolonged survival on PKC412/midostaurin [PDF]
, 2014 Mast cell leukemia (MCL) is a rare and aggressive form of systemic mastocytosis. There are approximately 50 reported cases since 1950s. MCL is refractory to cytoreduction chemotherapy and the average survival is only six months. We report a MCL case in a
Frater, John L +3 more
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Experimental and clinical study of the efficacy of medicines containing omega-3 and 6 polyunsaturated fatty acids, in the treatment of inflammatory skin diseases [PDF]
, 2018 Over the recent years, the attention of scientists regarding the search for alternative means of treatment, including local therapy, of inflammatory skin diseases, has been focused in recent years on medicines containing omega-3 and 6 polyunsaturated ...
Grebennikova, S. V., Maklyakov, Y. S.
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Case Reports in Medicine, 2015 The pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti ...
Sofie Lieberoth, Simon Francis Thomsen
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Mastocytosis: One Word for Different Diseases
Oncology and Therapy, 2018 Mastocytosis is a neoplastic disease originating from tissue infiltration by transformed mast cells. The diagnosis requires a high grade of suspicion due to the large variety of presenting symptoms. The World Health Organization classification recognizes
Marianna Criscuolo +3 more
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Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells [PDF]
, 2018 The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Ambrosio, Laura Fernanda +7 more
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