Results 81 to 90 of about 69,333 (214)

Skin Disease in Mastocytosis

, 2019
The hallmark of mastocytosis is the pathological accumulation of mast cells in various tissues. The skin is the most frequently affected organ, followed by bone marrow.
Manjaly Thomas, Zita-Rose, Zita-Rose Manjaly Thomas, Karin Hartmann, Hartmann, Karin   +3 more
core   +1 more source

Enhanced PIEZO1 expression in mast cells of mastocytosis skin lesions: Relevance to Darier's sign

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Yoshiaki Kobayashi, Nobuhiro Nakano, Nguyen Quoc Vuong Tran, Yuki Nakamura, Lisa Minai, Takashi Okamoto, Daiki Nakagomi, Tatsuki R. Kataoka, Tatsuyoshi Kawamura, Atsuhito Nakao   +9 more
wiley   +1 more source

Diagnosing Systemic Mastocytosis: State of the Art

International Journal of Laboratory Hematology, Volume 48, Issue 3, Page 551-560, June 2026.
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley   +1 more source

Challenges in the Diagnosis of Cutaneous Mastocytosis

Diagnostics
Background: Mastocytosis is characterized by an accumulation of clonal mast cells (MCs) in tissues such as the skin. Skin lesions in mastocytosis may be clinically subtle or heterogeneous, and giving the correct diagnosis can be difficult.
Knut Brockow, Rebekka Karolin Bent, Simon Schneider, Sophie Spies, Katja Kranen, Benedikt Hindelang, Zsuzsanna Kurgyis, Sigurd Broesby-Olsen, Tilo Biedermann, Clive E. Grattan   +9 more
doaj   +1 more source

Health inequities in pediatric anaphylaxis: A policy framework and call to action for equitable care from SIAIP allergy prevention commission

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
Abstract Pediatric anaphylaxis is a rapidly evolving and potentially fatal allergic reaction whose incidence is increasing worldwide, particularly among young children. Despite international guidelines identifying intramuscular epinephrine as the first‐line, life‐saving treatment, significant health inequities persist in the prevention, recognition ...
Carolina Grella, Angela Klain, Amelia Licari, Sara Manti, Francesca Mori, Francesca Galletta, Antonio Andrea Senatore, Leonardo Tomei, Michele Miraglia del Giudice, Gian Luigi Marseglia, Cristiana Indolfi, The SIAIP Primary and Secondary Prevention of Allergic Diseases Commission   +11 more
wiley   +1 more source

CD30 Expression in Neoplastic Mast Cells and the Presence of CD30+, CD3+, and PAX‐5+ Tumour‐Infiltrating Lymphocytes as Prognostic Markers in Canine Cutaneous Mast Cell Tumours

Veterinary and Comparative Oncology, Volume 24, Issue 2, Page 341-352, June 2026.
ABSTRACT Canine cutaneous mast cell tumour (MCT) is the most common skin neoplasm in dogs, with histopathology serving as both the diagnostic and primary prognostic tool. However, identifying reliable biomarkers is essential for improving clinical decision‐making.
Fernanda Ramalho Ramos, Janayna Maria Parente Serafim, Bethânia Almeida Gouveia, Pedro Luiz Porfirio Xavier, Juliano Rodrigues Sangalli, Heidge Fukumasu, Ricardo de Francisco Strefezzi   +6 more
wiley   +1 more source

CD30 in Systemic Mastocytosis [PDF]

, 2014
CD30 is a transmembrane receptor, normally not expressed by mast cells, which regulates proliferation/apoptosis and antibody responses. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play ...
Joanne N.G. Oude Elberink, Bjorn van Anrooij, Oude Elberink, H. N. G., Kluin-Nelemans, Johanna C., Philip M. Kluin, van Anrooij, Bjorn, Kluin, Philip M., Johanna C. Kluin-Nelemans   +7 more
core   +1 more source

Mastocytosis - diagnosis and classification

, 2009
Mastocytosis is a heterogeneous group of disorders with different severity and prognosis, which are characterized by excessively increased numbers of mast cells in the skin or in other tissues.
Brockow, K;Behrendt, H;Ring, J
core   +1 more source

Gastrointestinal tract involvement in systemic mastocytosis: a clinical case

Patologìâ
Mastocytosis is a group of rare heterogeneous diseases caused by excessive proliferation and accumulation of mast cells in various organs and systems.
Ya. S. Bereznytskyi, O. V. Simonova , T. Y. Boiko, H. V. Tuzko, H. S. Lapsar, S. A. Simonova   +5 more
doaj   +1 more source

Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab

Case Reports in Medicine, 2015
The pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti ...
Sofie Lieberoth, Simon Francis Thomsen
doaj   +1 more source