Results 71 to 80 of about 69,333 (214)
Journal of Immunology Research, 2019 Background. Mastocytosis is a condition characterized by the expansion and accumulation of mast cells (MCs) in various organs. The symptoms are related to the increased release of MC-derived mediators that exert local and distant effects.
Anne Lise Ferrara +9 more
doaj +1 more source
Urticaria pigmentosa and systemic mastocytosis
, 2023 Key Clinical Message: Additional investigations for systemic involvement should be initiated once the diagnosis of cutaneous mastocytosis has been established in an adult patient.
Cyrus C. Hsia +3 more
core +2 more sources
Anaphylactic transfusion reaction to group B platelets related to alpha‐gal syndrome: A case report
Transfusion, EarlyView.Abstract Background Alpha‐gal syndrome (AGS), a distinct form of IgE‐mediated hypersensitivity to the carbohydrate galactose‐α‐1,3‐galactose (α‐Gal), typically occurs after repeated tick bites and leads to allergic reactions after ingestion of mammalian meat.
Oscar Andre Hinojosa +2 more
wiley +1 more source
Kinetic Fingerprints as Mechanistic and Clinical Roadmaps Across KIT Activation States
ChemMedChem, Volume 21, Issue 11, 15 June 2026.Kinetic profiling of 172 compounds across KIT conformations—including D816V—reveals kinetic fingerprints that predict efficacy, selectivity, resistance, and inhibitors’ ability to stabilize key regulatory elements. Far from a secondary metric, binding kinetics provide mechanistic insights beyond affinity, offering a powerful framework for rational drug
Ana Corrionero +7 more
wiley +1 more source
Dermatoscopic findings of urticaria pigmentosa [PDF]
Anais Brasileiros de Dermatologia, 2013 Mastocytosis is a rare disease characterized by proliferation and accumulation of mast cells in various organs. The maculopapular cutaneus mastocytosis is divided into three subtypes: papular/plaque variant, urticaria pigmentosa and eruptive macular ...
Marcela Duarte Benez Miller +4 more
doaj +1 more source
Preclinical human models and emerging therapeutics for advanced systemic mastocytosis
Haematologica, 2018 Mastocytosis is a term used to denote a group of rare diseases characterized by an abnormal accumulation of neoplastic mast cells in various tissues and organs.
Michel Arock +10 more
doaj +1 more source
Role of Cysteinyl Leukotrienes in Food Allergy and Anaphylaxis: A Potential Therapeutic Target
Allergy, EarlyView.
A. Weingaertner, T. Eiwegger
wiley +1 more source
Veterinary Record Open, Volume 13, Issue 1, June 2026.Abstract Background Animal cancer registry data are important for monitoring animal health, for prevention and research in veterinary medicine, and for comparative oncology. Since people and animals share the same environment and are exposed to many common risk factors, cancer patterns in animals may have a sentinel function for human health.
Claudio Trentin +10 more
wiley +1 more source
A Case for Anti‐IgE Vaccination
Allergy, Volume 81, Issue 6, Page 2001-2013, June 2026.ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff +3 more
wiley +1 more source