Results 61 to 70 of about 6,446 (159)

Case-control cohort study of patients' perceptions of disability in mastocytosis. [PDF]

PLoS ONE, 2008
BackgroundIndolent forms of mastocytosis account for more than 90% of all cases, but the types and type and severity of symptoms and their impact on the quality of life have not been well studied.
Olivier Hermine, Olivier Lortholary, Phillip S Leventhal, Adeline Catteau, Frédérique Soppelsa, Cedric Baude, Annick Cohen-Akenine, Fabienne Palmérini, Katia Hanssens, Ying Yang, Hagay Sobol, Sylvie Fraytag, David Ghez, Felipe Suarez, Stéphane Barete, Philippe Casassus, Beatrice Sans, Michel Arock, Jean Pierre Kinet, Patrice Dubreuil, Alain Moussy   +20 more
doaj   +1 more source

Environmental Changes and Their Effect on the Airway Microbiome: Implications for Airway Diseases

Allergy, EarlyView.
ABSTRACT Obstructive airway diseases, including asthma and chronic obstructive pulmonary disease (COPD), represent the two major chronic airway inflammatory diseases. In both conditions, the airways are exposed to a variety of microbial and environmental stimuli.
Georgios Rentzos, Evangelia Fouka, Nikolaos Lazarinis, Theo Gülen, Patricia Ramos‐Ramirez, Lauren Flynn, Stelios Loukides, Paraskevi Xepapadaki, Nikolaos G. Papadopoulos, Anders Lindén, Apostolos Bossios   +10 more
wiley   +1 more source

Cutaneous mastocytosis [PDF]

, 2020
Review on cutaneous mastocytosis, with data on clinics, pathology, and involved ...
Chisholm, Karen M
core   +1 more source

Depression in patients with mastocytosis: prevalence, features and effects of masitinib therapy. [PDF]

PLoS ONE, 2011
Depression in patients with mastocytosis is often reported but its prevalence and characteristics are not precisely described. In addition, the impact of therapies targeting mast cells proliferation, differentiation and degranulation on psychic symptoms ...
Daniela Silva Moura, Serge Sultan, Sophie Georgin-Lavialle, Nathalie Pillet, François Montestruc, Paul Gineste, Stéphane Barete, Gandhi Damaj, Alain Moussy, Olivier Lortholary, Olivier Hermine   +10 more
doaj   +1 more source

An Extended Transcriptomic Landscape of Human Skin Mast Cells: Unveiling Lineage‐Specific Noncoding RNA Dynamics in FcεRI Activation

Allergy, EarlyView.
FcεRI cross‐linking triggers widespread transcriptional reprogramming in human skin mast cells (> 5000 genes, > 6400 promoters, and 48 novel mast cell‐enriched lncRNAs). Breast skin and foreskin mast cells share core transcriptional programs but differ selectively in tryptase isoenzymes and IL‐8/IL‐1RA release.
Gürkan Bal, Kristin Franke, Stefan Frischbutter, Shiva Raj Tripathi, Kayoko Yasuzawa, Jordan A. Ramilowski, Michihira Tagami, Takeya Kasukawa, Michiel de Hoon, Jay W. Shin, Piero Carninci, Torsten Zuberbier, Magda Babina   +12 more
wiley   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Colonic Mast Cell Density and Diarrhoea: Evidence Against a Threshold Effect in Biopsies From 3508 Patients

Alimentary Pharmacology &Therapeutics, EarlyView.
A large data base of colonoscopies was analysed for mast cells. The data do not show a relationship between diarrhoea and elevated mast cells in the colonic mucosa. This study provides real‐world evidence against the routine diagnostic use of colonic mast cell quantification for the evaluation of diarrhoea.
Marlena Langreiter, Robert M. Genta, Philipp Schreiner   +2 more
wiley   +1 more source

Tryptase Locus Variation Contributes to Normal‐Range Basal Serum Tryptase Variability and Is Associated With Anaphylaxis

Clinical &Experimental Allergy, EarlyView.
Tryptase locus variation explains normal‐range baseline serum tryptase differences and is associated with Hymenoptera venom anaphylaxis, independent of clonal mast cell disease and HαT. ABSTRACT Background Increased basal serum tryptase level (BST) is associated with anaphylaxis.
Manca Svetina, Jonathan J. Lyons, Peter Kopač, Julij Šelb, Mitja Košnik, Matija Rijavec, Peter Korošec   +6 more
wiley   +1 more source

Cofactors in Anaphylaxis: Insights From the European Anaphylaxis Registry

Clinical &Experimental Allergy, EarlyView.
Forty‐nine per cent of reactions reported suspected cofactors (26% of children/adolescents, 59% of adults). Adjusted odds ratios for reaction severity increased with increasing number of suspected cofactors. Consistent effects for individual suspected cofactors were only observed for acute infections (children) and alcohol (adults with food‐induced ...
Margitta Worm, Sabine Dölle‐Bierke, Guillaume Pouessel, Franziska Ruëff, Karin Hartmann, Claudia Pföhler, Maria Beatrice Bilò, Nicola Wagner, Nikolaos G. Papadopoulos, Lars Lange, Andrea Bauer, Johannes Trück, Paul J. Turner, Veronika Höfer   +13 more
wiley   +1 more source

Altered Metabolism of Phospholipases, Diacylglycerols, Endocannabinoids, and N-Acylethanolamines in Patients with Mastocytosis

Journal of Immunology Research, 2019
Background. Mastocytosis is a condition characterized by the expansion and accumulation of mast cells (MCs) in various organs. The symptoms are related to the increased release of MC-derived mediators that exert local and distant effects.
Anne Lise Ferrara, Fabiana Piscitelli, Angelica Petraroli, Roberta Parente, Maria Rosaria Galdiero, Gilda Varricchi, Giancarlo Marone, Massimo Triggiani, Vincenzo Di Marzo, Stefania Loffredo   +9 more
doaj   +1 more source