Results 41 to 50 of about 6,446 (159)

Mastocytosis – an update [PDF]

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2010
SummaryMastocytosis (MC) encompasses a range of disorders characterized by a clonal, pathological accumulation of mast cells having a somatic activating mutation of the tyrosine kinase receptor Kit (exon 17, codon 816; D816V) in more than 90 % of adult patients. The mutation is much less common in children. Skin and bone marrow are most often affected.
Amon, Ulrich, Hartmann, Karin, Horny, Hans-Peter, Nowak, Anna   +3 more
openaire   +3 more sources

PD-1 Regulates the Growth of Human Mastocytosis Cells

Allergology International, 2013
Background: Programmed death-1 (PD-1) is a marker for human neoplastic T cells. Here, we evaluated whether or not PD-1 was also a marker for human mastocytosis, and explored the role of PD-1 in human mastocytosis cells.
Tatsuki R. Kataoka, Masakazu Fujimoto, Koki Moriyoshi, Itsuko Koyanagi, Chiyuki Ueshima, Fumihiko Kono, Tatsuaki Tsuruyama, Yoshimichi Okayama, Chisei Ra, Hironori Haga   +9 more
doaj   +1 more source

The diagnostic workup for systemic mastocytosis differs from consensus recommendations: Results of a worldwide survey

World Allergy Organization Journal, 2023
Objective: Mastocytosis is a complex disorder affecting various organs. The diagnostic workup can be challenging and requires a multidisciplinary approach including the use of uncommon tests.
Polina Pyatilova, MD, Jonathan A. Bernstein, MD, Felix Aulenbacher, Msc, Mario Sanchez Borges, MD, Saša Dimitrijević, PhD, Gerard Hoehn, PhD, Marcus Maurer, MD, Pavel Kolkhir, MD, Frank Siebenhaar, MD   +8 more
doaj   +1 more source

Proposed global prognostic score for systemic mastocytosis: a retrospective prognostic modelling study [PDF]

, 2021
[Background]: Several risk stratification models have been proposed in recent years for systemic mastocytosis but have not been directly compared. Here we designed and validated a risk stratification model for progression-free survival (PFS) and overall ...
Gotlib, Jason, Duyster, Justus, Caldas, Carolina, Valent, Peter, Orfao, Alberto, Shoumariyeh, Khalid, Jawhar, Mohamad, Senent, Leonor, Schmitt-Graeff, Annette, Jara-Acevedo, Maria, Martín-Sánchez, Guillermo, Bañas, Helena, Sperr, Wolfgang R., Tanasi, Ilaria, Gener-Ricós, Georgina, Colado, Enrique, Greiner, Georg, García-Montero, Andrés, Nuñez-García, Amanda, Xicoy, Blanca, Mayado, Andrea, Henriques, Ana, Schwaab, Juliana, Jurado-Chacón, Manuel, Álvarez-Twose, Iván, Fernández-Giménez, Carlos, Mora-Casterá, Elvira, Reiter, Andreas, Zanotti, Roberta, Bonadonna, Patrizia, Muñoz-González, J. I., Luna, Irene, Sánchez-Muñoz, Laura, Olivieri, Francesco, Pérez-Pons, Alba, Perkins, Cecelia, García-Montero, Andrés C., Muñoz-González, Javier I., Schmitt-Gräff, Annette   +38 more
core   +1 more source

Mastocitosis

Revista Alergia México, 2015
Mastocytosis is one of the eight subcategories of the myeloproliferative neoplasms of the classification of lymphoid and hematopoietic tissues’ tumors of 2008 of World Health Organization; it is an heterogeneous group of myeloproliferative diseases characterized by the excessive proliferation of atypical mastocytes in morphological and immunophenotype ...
González Díaz, Sandra Nora, Palma Gomez, Samuel, Pérez Vanzzini, Rafael, Arias Cruz, Alfredo   +3 more
openaire   +3 more sources

Bullous mastocytosis: a Case Report

Journal of the Egyptian Women’s Dermatologic Society
Mastocytosis is a disorder characterized by abnormal mast cell proliferation. The skin is the most common site of involvement. Extracutaneous involvement occurs in systemic mastocytosis with infiltrations in the gastrointestinal tract, lymph nodes, bone ...
Galal El Enany, Noha Nagui, Hanan Nada, Mona R.E. Abdel-Halim, Iman Sany, Ahmad Nada, Omar El Ghanam, Mona M. Korany   +7 more
doaj   +1 more source

Mast Cell Sarcoma of the Retroperitoneum With Concurrent Systemic Mastocytosis and an Undisclosed Associated Hematologic Neoplasm: A Case Report

Clinical Pathology, 2022
Mastocytosis is a rare disorder affecting both children and adults by gathering of functionally defective mast cells in the body’s tissues. The World Health Organization (WHO) classified mastocytosis into cutaneous mastocytosis, systemic mastocytosis (SM)
Ing Chen, Jia-Bin Liao, Jung-Chia Lin, Pin-Pen Hsieh, Ming-Yun Hsieh   +4 more
doaj   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Mastocytosis in Pregnancy

Taiwanese Journal of Obstetrics and Gynecology, 2010
Mastocytosis is a rare disorder characterized by abnormal accumulation of mast cells in various organs. Clinical complaints include pruritus, cutaneous flushing, dyspepsia, and episodes of anaphylaxis, and are usually the result of local and systemic mast cell mediator release. The triggers include a variety of factors including drugs, exercise, stress,
TARHAN, Irfan, ALTINKAYA, Sunduz Ozlem, MADENDAG, Ilknur Col, Madendag, Yusuf, DANISMAN, Nuri   +4 more
openaire   +4 more sources

Epidemiology of mastocytosis: a population-based study (Sweden)

Acta Oncologica
Background: Mastocytosis is a disease characterized by accumulation of aberrant mast cells and mediator-related symptoms and is divided into systemic mastocytosis (SM) and cutaneous mastocytosis (CM).
Anna Bergström, Hans Hägglund, Anders Berglund, Gunnar Nilsson, Mats Lambe   +4 more
doaj   +1 more source