Results 41 to 50 of about 74,581 (201)

Mastocytosis: Fertility and Pregnancy Management in a Rare Disease

Frontiers in Oncology, 2022
Mastocytosis encompasses a subset of rare diseases, characterized by the presence and accumulation of abnormal neoplastic MC in various organ systems, including skin, bone marrow, spleen and gastrointestinal tract.
Jacqueline Ferrari, Pietro Benvenuti, Elisa Bono, Elisa Bono, Nicolas Fiorelli, Chiara Elena   +5 more
doaj   +1 more source

Successful treatment with Omalizumab of a child affected by Systemic Mastocytosis: clinical and biological implications

Italian Journal of Pediatrics, 2023
Background Pediatric Mastocytosis is a rare and heterogeneous disease, characterized by accumulation of mast cells in the skin (Cutaneous Mastocytosis) and/or, less frequently, in other organs, mainly liver, spleen, bone marrow, lymph nodes and ...
Grazia Bossi, Valeria Brazzelli, Mara De Amici, Daniela Pietra, Chiara Raviola, Matteo Naso, Corrado Regalbuto, Federica Boselli, Valeria Fortina, Gian Luigi Marseglia   +9 more
doaj   +1 more source

Splenic Mastocytosis [PDF]

Blood, 1958
Abstract 1. A patient with splenic mastocytosis who had hypersplenism, periodic flushing and clotting defects is presented. 2. A correlation is shown between mastocytosis and elevated histamine and heparin levels in the spleen. 3. The patient is well nine months after splenectomy. 4.
N, ENDE, E I, CHERNISS
openaire   +2 more sources

Mastocytosis – an update [PDF]

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2010
SummaryMastocytosis (MC) encompasses a range of disorders characterized by a clonal, pathological accumulation of mast cells having a somatic activating mutation of the tyrosine kinase receptor Kit (exon 17, codon 816; D816V) in more than 90 % of adult patients. The mutation is much less common in children. Skin and bone marrow are most often affected.
Amon, Ulrich, Hartmann, Karin, Horny, Hans-Peter, Nowak, Anna   +3 more
openaire   +3 more sources

PD-1 Regulates the Growth of Human Mastocytosis Cells

Allergology International, 2013
Background: Programmed death-1 (PD-1) is a marker for human neoplastic T cells. Here, we evaluated whether or not PD-1 was also a marker for human mastocytosis, and explored the role of PD-1 in human mastocytosis cells.
Tatsuki R. Kataoka, Masakazu Fujimoto, Koki Moriyoshi, Itsuko Koyanagi, Chiyuki Ueshima, Fumihiko Kono, Tatsuaki Tsuruyama, Yoshimichi Okayama, Chisei Ra, Hironori Haga   +9 more
doaj   +1 more source

Diagnostic Evaluation of Hypersensitivity Reactions to Antibiotics in a Large Cohort of Mastocytosis Patients

Diagnostics, 2023
Background: Anaphylactic reactions are a well-known feature of mastocytosis, particularly in relation to hymenoptera venom stings. Although data on the frequency of drug hypersensitivity reactions is limited in mastocytosis, it is hypothesized that these
Jesper Jarkvist, Theo Gülen
doaj   +1 more source

The diagnostic workup for systemic mastocytosis differs from consensus recommendations: Results of a worldwide survey

World Allergy Organization Journal, 2023
Objective: Mastocytosis is a complex disorder affecting various organs. The diagnostic workup can be challenging and requires a multidisciplinary approach including the use of uncommon tests.
Polina Pyatilova, MD, Jonathan A. Bernstein, MD, Felix Aulenbacher, Msc, Mario Sanchez Borges, MD, Saša Dimitrijević, PhD, Gerard Hoehn, PhD, Marcus Maurer, MD, Pavel Kolkhir, MD, Frank Siebenhaar, MD   +8 more
doaj   +1 more source

Biochemical markers predictive for bone marrow involvement in systemic mastocytosis

Haematologica, 2008
Systemic mastocytosis is characterized by bone marrow involvement, which requires a bone marrow biopsy for diagnostic work-up. We questioned whether bone marrow involvement could be predicted using biochemical markers.
Marjolein L. Donker, Jasper J. van Doormaal, Frederiek F. van Doormaal, Philip M. Kluin, Eveline van der Veer, Jan G.R. de Monchy, Ido P. Kema, Hanneke C. Kluin-Nelemans   +7 more
doaj   +1 more source

Mast Cell Sarcoma of the Retroperitoneum With Concurrent Systemic Mastocytosis and an Undisclosed Associated Hematologic Neoplasm: A Case Report

Clinical Pathology, 2022
Mastocytosis is a rare disorder affecting both children and adults by gathering of functionally defective mast cells in the body’s tissues. The World Health Organization (WHO) classified mastocytosis into cutaneous mastocytosis, systemic mastocytosis (SM)
Ing Chen, Jia-Bin Liao, Jung-Chia Lin, Pin-Pen Hsieh, Ming-Yun Hsieh   +4 more
doaj   +1 more source

Bullous mastocytosis: a Case Report

Journal of the Egyptian Women’s Dermatologic Society
Mastocytosis is a disorder characterized by abnormal mast cell proliferation. The skin is the most common site of involvement. Extracutaneous involvement occurs in systemic mastocytosis with infiltrations in the gastrointestinal tract, lymph nodes, bone ...
Galal El Enany, Noha Nagui, Hanan Nada, Mona R.E. Abdel-Halim, Iman Sany, Ahmad Nada, Omar El Ghanam, Mona M. Korany   +7 more
doaj   +1 more source