Results 21 to 30 of about 69,333 (214)

Mastocytosis [PDF]

open access: yesImmunology and Allergy Clinics of North America, 2014
Mastocytosis is a disorder of abnormal mast cell proliferation, with clinical features that include flushing, pruritus, abdominal pain, diarrhea, hypotension, syncope, and musculoskeletal pain. These features are the result of mast cell mediator release and infiltration into target organs.
Melody C, Carter   +2 more
openaire   +2 more sources

Proposed global prognostic score for systemic mastocytosis: a retrospective prognostic modelling study [PDF]

open access: yes, 2021
[Background]: Several risk stratification models have been proposed in recent years for systemic mastocytosis but have not been directly compared. Here we designed and validated a risk stratification model for progression-free survival (PFS) and overall ...
Cecelia Perkins   +71 more
core   +1 more source

Recalcitrant Cutaneous Mastocytosis Treated With Genetically Informed Targeted Therapy: A Case Report

open access: yesInternational Journal of Dermatology and Venerology, 2023
Introduction:. Mastocytosis, a clonal proliferation of mast cells commonly involving the skin and bone marrow, has a varied clinical presentation ranging from cutaneous lesions to systemic disease.
Laura Gleason   +7 more
doaj   +1 more source

How “benign” is cutaneous mastocytosis? A Danish registry-based matched cohort study

open access: yesInternational Journal of Women's Dermatology, 2020
Background: There are limited estimates of the incidence rates (IRs) of mastocytosis, and only a few studies have addressed the long-term consequences of living with these diagnoses.
Line Kibsgaard, MD, PhD   +5 more
doaj   +1 more source

Increased TIM-3 and GAL-9 serum levels in patients with advanced systemic mastocytosis. [PDF]

open access: yes, 2023
BACKGROUND Systemic mastocytosis is characterized by expansion of clonal mast cells in various tissues. Several biomarkers with diagnostic and therapeutic potential have recently been characterized in mastocytosis, such as the serum marker tryptase ...
Peter Valent   +19 more
core   +1 more source

SWATH-MS identification of CXCL7, LBP, TGFβ1 and PDGFRβ as novel biomarkers in human systemic mastocytosis

open access: yesScientific Reports, 2022
Mastocytosis is a rare myeloproliferative disease, characterised by accumulation of neoplastic mast cells in one or several organs. It presents as cutaneous or systemic.
R. L. J. Graham   +5 more
doaj   +1 more source

Mastocytosis

open access: yesAmerican Journal of Clinical Pathology, 2020
Abstract Objectives The 2019 Workshop of the Society for Hematopathology/European Association for Haematopathology received and reviewed cases covering the spectrum of mastocytosis and related diseases, including morphologic mimics, focusing on recent updates and relevant findings for pathologists.
Alexandar, Tzankov   +11 more
openaire   +2 more sources

Delayed Diagnosis of Indolent Systemic Mastocytosis as the Cause of Unexplained Skin Rash: A Case Report

open access: yesCase Reports in Oncology, 2023
Mastocytosis is a heterogeneous group of disorders in which mast cells exhibit clonal proliferation that infiltrates one or more organs. In cutaneous mastocytosis, the mast cells infiltrate the skin only, whereas systemic mastocytosis is diagnosed when ...
Awni Alshurafa   +4 more
doaj   +1 more source

Clinical Cases: Diagnostic Errors of Mastocytosis Cutaneous Forms in Children

open access: yesПедиатрическая фармакология, 2022
Background. Mastocytosis refers to the group of rare diseases with pathological mast cells accumulation in tissues. Although diagnosis of cutaneous mastocytosis is not usually difficult for experienced physicians, misdiagnosis is possible.Clinical cases ...
Lianna K. Aslamazyan   +4 more
doaj   +1 more source

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