Results 31 to 40 of about 74,252 (184)
Extracellular Vesicles: A Mailcoach From Mast Cell to Other Cell Species [PDF]
ABSTRACT Background Mast cells (MCs) are pivotal immune cells. Beyond soluble mediators, mast cell‐derived extracellular vesicles (MC‐EVs) are crucial for intercellular communication. MC‐EV heterogeneity, influenced by cellular activation and microenvironment, drives diverse biological roles.
Zhang B, Sun Y, Jiang T, Long R, Guo Y.
europepmc +2 more sources
International consensus on (ICON) anaphylaxis [PDF]
ICON: Anaphylaxis provides a unique perspective on the principal evidence-based anaphylaxis guidelines developed and published independently from 2010 through 2014 by four allergy/immunology organizations.
Alvarez-Twose +137 more
core +3 more sources
A unique presentation of pulmonary disease in advanced systemic mastocytosis, proven by the presence of mast cells in bronchoalveolar lavage: A case report [PDF]
Background: Systemic mastocytosis is a rare myeloproliferative disease characterized by the uncontrolled proliferation of aberrant mast cells. It has varying clinical manifestations.
Broijl, A. (Annemiek) +2 more
core +2 more sources
PD-1 Regulates the Growth of Human Mastocytosis Cells
Background: Programmed death-1 (PD-1) is a marker for human neoplastic T cells. Here, we evaluated whether or not PD-1 was also a marker for human mastocytosis, and explored the role of PD-1 in human mastocytosis cells.
Tatsuki R. Kataoka +9 more
doaj +1 more source
Objective: Mastocytosis is a complex disorder affecting various organs. The diagnostic workup can be challenging and requires a multidisciplinary approach including the use of uncommon tests.
Polina Pyatilova, MD +8 more
doaj +1 more source
Kit receptor tyrosine kinase dysregulations in feline splenic mast cell tumours [PDF]
This study investigated Ki t receptor dysregulations (cytoplasmic immunohistochemical expression and/or c-KIT mutations) in cats a\ufb00ected with splenic mast cell tumours. Twenty-two cats were included.
Amagai +32 more
core +1 more source
Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder [PDF]
Although more than 90% systemic mastocytosis (SM) patients express gain of function mutations in the KIT receptor, recent next generation sequencing has revealed the presence of several additional genetic and epigenetic mutations in a subset of these ...
Chatterjee, Anindya +2 more
core +2 more sources
Routine abdominal ultrasonography has limited value in the care for patients with indolent systemic mastocytosis [PDF]
Objectives: Systemic mastocytosis (SM) is a myeloproliferative disease characterized by the accumulation of aberrant mast cells. Since advanced subtypes of SM can lead to organ dysfunction and shortened survival, timely recognition of progressive disease
Daele, P.L.A. (Paul) van +4 more
core +2 more sources
Mastocytosis is a rare disorder affecting both children and adults by gathering of functionally defective mast cells in the body’s tissues. The World Health Organization (WHO) classified mastocytosis into cutaneous mastocytosis, systemic mastocytosis (SM)
Ing Chen +4 more
doaj +1 more source
Regulation of mast cell function and survival in health and disease [PDF]
Mast cells are sentinels of danger but they are also the major effector cells in allergic disease causing the well-known allergic symptoms caused by their mediators such as histamine and prostaglandin D2 that are released upon activation. Mastocytosis is
Lyberg, Katarina
core +1 more source

