Results 141 to 150 of about 766,213 (248)

Novel Allocation Strategies Can Boost Kidney Exchange Programs: A Monte Carlo Simulation. [PDF]

Transpl Int
Klaassen MF, de Klerk M, Baas MC, Bouwsma H, Bungener LB, Christiaans MHL, Dollevoet T, Glorie K, Heidt S, Hemke AC, de Jong MFC, Kal-van Gestel JA, Kho MML, Langereis JD, van der Pant KAMI, Ranzijn CM, Roelen DL, Spierings E, Voorter CEM, van de Wetering J, van Zuilen AD, Roodnat JI, de Weerd AE.   +22 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Simulation of prospective PIRCHE-II molecular matching in Canada: a feasibility study. [PDF]

Front Immunol
Sherwood KR, Günther OP, Fenninger F, Tran J, Lan J, Niemann M, Sapir-Pichhadze R, Keown PA.   +7 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Estimated Impact of Pressure to Conceive on Maternal Depression in Lesotho: A Quasi-experimental Propensity Score Matching using DHS Data. [PDF]

Arch Womens Ment Health
Jejaw M, Kelkay JM, Demissie KA, Hagos A, Teshale G, Baykemagn ND, Tadele A, Tafere TZ, Aschalew AY, Yehuala TZ.   +9 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Masked and elusive: congruency fails in video-to-photo face matching. [PDF]

Cogn Res Princ Implic
Sagana A, Zhang M, Bekemeier L, Nelissen E, Sauerland M.   +4 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Limb Position Sense Across Multiple Proprioceptive Tasks in Healthy Adults. [PDF]

Ann Rehabil Med
Yun SJ, Park S, Oh BM, Seo HG.
europepmc   +1 more source