Results 141 to 150 of about 3,156,718 (320)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Automated generation of comparator patients in the electronic medical record

open access: yesLearning Health Systems
Background Well‐designed randomized trials provide high‐quality clinical evidence but are not always feasible or ethical. In their absence, the electronic medical record (EMR) presents a platform to conduct comparative effectiveness research, central to ...
Joseph Rigdon   +6 more
doaj   +1 more source

Unmanned Aerial Vehicle-Based Structural Health Monitoring and Computer Vision-Aided Procedure for Seismic Safety Measures of Linear Infrastructures

open access: yesSensors
Computer vision in the structural health monitoring (SHM) field has become popular, especially for processing unmanned aerial vehicle (UAV) data, but still has limitations both in experimental testing and in practical applications.
Luna Ngeljaratan   +2 more
doaj   +1 more source

Tree matchings

open access: yesJournal of Graph Theory, 2019
AbstractAn ‐matching in a bipartite graph is a subset of the edges such that each component of is a tree with at most edges and each vertex in has neighbours in . We give sharp sufficient neighbourhood‐conditions for a bipartite graph to contain an ‐matching. As a special case, we prove a conjecture of Bennett, Bonacina, Galesi, Huynh, Molloy and
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Investigating SEM-contour to CD-SEM matching

open access: green, 2021
François Weisbuch   +5 more
openalex   +2 more sources

An Improved Bytewise Approximate Matching Algorithm Suitable for Files of Dissimilar Sizes [PDF]

open access: gold, 2020
Víctor Gayoso Martínez   +2 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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