Results 141 to 150 of about 2,234,974 (362)
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Labor market matching with heterogeneous job seekers in China [PDF]
Our study provides empirical evidence for matching functions with three heterogeneous groups of job seekers in China, and bridges the gap of matching function estimation of the Chinese labor market.
Yang Liu
core
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
On the uniqueness of probability matching priors [PDF]
Probability matching priors are priors for which Bayesian and frequentist inference, in the form of posterior quantiles, or confidence intervals, agree to some order of approximation.
Staicu, A-M, Reid, N, Reid, Nancy
core
AbstractAn ‐matching in a bipartite graph is a subset of the edges such that each component of is a tree with at most edges and each vertex in has neighbours in . We give sharp sufficient neighbourhood‐conditions for a bipartite graph to contain an ‐matching. As a special case, we prove a conjecture of Bennett, Bonacina, Galesi, Huynh, Molloy and
openaire +4 more sources
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Assortative Matching and Reputation [PDF]
Consider Becker's classic 1963 matching model, with unobserved fixed types and stochastic publicly observed output. If types are complementary, then matching is assortative in the known Bayesian posteriors (the 'reputations').
Axel Anderson, Lones Smith
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Aggregate Matching Function. The Case of Poland [PDF]
The main goal of this paper is to analyze the matching function in the Polish labour market in 1994-2008. Matching function is the relationship between outflows from unemployment to employment and the number of unemployed persons and vacancies as well as
Sylwia Roszkowska
core

