Results 121 to 130 of about 458,841 (313)
Probability Matching and Reinforcement Learning* [PDF]
Probability matching occurs when an action is chosen with a frequency equivalent to the probability of that action being the best choice. This sub-optimal behavior has been reported repeatedly by psychologist and experimental economist.
Javier Rivas
core
Matching JWST Ultraviolet Luminosity Functions with Refined ΛCDM Halo Models
The Astrophysical JournalThe James Webb Space Telescope (JWST) has unveiled a population of unexpectedly massive and luminous galaxies at redshifts z ≳ 7, posing a significant challenge to the standard Lambda cold dark matter (ΛCDM) cosmological paradigm.
Saeed Fakhry +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Estimating Matching Games with Transfers [PDF]
Economists wish to use data on matches to learn about the structural primitives that govern sorting. I show how to use equilibrium data on who matches with whom for semiparametric estimation of match production functions in many-to-many, two-sided ...
Jeremy T. Fox
core
Volatile hiring: uncertainty in search and matching models.
J Monet Econ, 2021 Den Haan WJ, Freund LB, Rendahl P.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Information criteria for impulse response function matching estimation of DSGE models [PDF]
We propose a new information criterion for impulse response function matching estimators of the structural parameters of macroeconomic models. The main advantage of our procedure is that it allows the researcher to select the impulse responses that are ...
Barbara Rossi +3 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
A Survey of Text-Matching Techniques
InformationText matching, as a core technology of natural language processing, plays a key role in tasks such as question-and-answer systems and information retrieval.
Peng Jiang, Xiaodong Cai
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source