Results 111 to 120 of about 7,531,042 (311)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Testing theories of labour market matching [PDF]
This paper estimates a model of two-sided search using micro-level data for a well-defined labour market. It examines the assumption of random matching and contrasts it with the stock-flow (or non-random) matching model of Coles and collaborators.
Upward, Richard +3 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Assortative Matching and Reputation [PDF]
Consider Becker's classic 1963 matching model, with unobserved fixed types and stochastic publicly observed output. If types are complementary, then matching is assortative in the known Bayesian posteriors (the 'reputations').
Axel Anderson, Lones Smith
core
Parameterized Matching in the Streaming Model
, 2011 19 pages, 3 ...
Markus Jalsenius +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Multivariate and Propensity Score Matching Software with Automated Balance Optimization: The Matching package for R [PDF]
Matching is an R package which provides functions for multivariate and propensity score matching and for finding optimal covariate balance based on a genetic search algorithm.
Jasjeet S. Sekhon
core
Conceptual Level and Program Openness: Some Data on Matching Models
Canadian Journal of Education, 1977 Après avoir regroupé élèves et enseignants en fonction de leur niveau de conceptualisation, on étudie les conséquences de ce regroupement sur les attitudes des élèves et sur le respect qu'ils se portent.
D.I. Allen
doaj +2 more sources
Enhancing biomarker based oncology trial matching using large language models
npj Digital MedicineClinical trials are an essential component of drug development for new cancer treatments, yet the information required to determine a patient’s eligibility for enrollment is scattered in large amounts of unstructured text.
Nour Alkhoury +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source