Results 91 to 100 of about 458,841 (313)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Evaluation of Digital Surface Models by Semi-Global Matching
, 2010 This paper considers a processing chain for automatically creating high resolution digital surface models and true ortho-images from aerial and satellite image data.
Hirschmüller, Heiko, Bucher, Tilman
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A Theoretical Foundation for Bilateral Matching Mechanisms [PDF]
This work introduces a rigorous set-theoretic foundation of bilateral matching mechanisms and studies their properties in a systematic manner. By providing a unified framework to study ilateral matching mechanisms, we formalize how different spatial ...
G. Camera, C.D. Aliprantis
core
Matching Game Preferences Through Dialogical Large Language Models: A Perspective
Applied SciencesThis perspective paper explores the future potential of “conversational intelligence” by examining how Large Language Models (LLMs) could be combined with GRAPHYP’s network system to better understand human conversations and preferences.
Renaud Fabre +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Does bargaining matter in the small firm's matching Mmodel? [PDF]
In this article, the authors use a stylized model of the labor market to investigate the effects of three alternative and well-known bargaining solutions.
Malherbet, Franck +2 more
core
A Novel Map Matching Method Based on Improved Hidden Markov and Conditional Random Fields Model
International Journal of Digital EarthAiming at the inherent “labeling bias” problem of Hidden Markov Models (HMMs) in the process of low-frequency sampling rate GPS trajectory map matching, this paper proposes a map matching method that combines HMMs and Conditional Random Field Models ...
Wei Li +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source