Results 111 to 120 of about 522,025 (259)

Two-Sided Matching and Spread Determinants in the Loan Market [PDF]

Empirical work on bank loans typically regresses loan spreads (markups of loan interest rates over a benchmark rate) on observed characteristics of banks, firms, and loans.
Jiawei Chen
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Matching the gold standard: Comparing experimental and non-experimental evaluation techniques for a geographically targeted program [PDF]

We compare non-experimental impact estimates based on matching methods with those from a randomized evaluation to determine whether the non-experimental approach can “match” the so-called gold standard.
John Maluccio, Sudhanshu Handa
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Equivalence class formation in 11-month-old pre-linguistic infants

Acta Colombiana de Psicología, 2017
Several studies have attempted to assess the role of naming in the emergence of equivalence relations, but results are inconsistent; on the one hand, there are reports of equivalence emerging without naming and on the other hand, some authors claim that ...
Adriana Gabriela Quezada Velázquez, María Antonia Padilla Vargas, Carlos Javier Flores Aguirre   +2 more
doaj  

Multivariate and Propensity Score Matching Software with Automated Balance Optimization: The Matching package for R

Matching is an R package which provides functions for multivariate and propensity score matching and for finding optimal covariate balance based on a genetic search algorithm.
Jasjeet S. Sekhon
core  

The wage effects of entering motherhood: a within-firm matching approach [PDF]

We analyze the wage effects of employment breaks of women entering motherhood using a novel within-firm matching approach where mothers? wages upon return to the job are compared with those of their female colleagues within the same firm.
Wolf, Elke, Bender, Stefan, Beblo, Miriam   +2 more
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

EL PAPEL DE LA RETROALIMENTACIÓN Y LA AUSENCIA O PRESENCIA DE INSTRUCCIONES EN LA ELABORACIÓN DE DESCRIPCIONES EN TAREAS DE DISCRIMINACIÓN CONDICIONAL

Acta Colombiana de Psicología
La función de las reglas e instrucciones para facilitar, mantener o modificar la conducta de los individuos se ha explorado ampliamente y en una gran variedad de tareas; ambas, independientemente de las propiedades y características que se les atribuyan,
ALEJANDRA PAOLA GUERRERO RADILLO, GERARDO ORTIZ RUEDA   +1 more
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source