Results 31 to 40 of about 522,025 (259)
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
In a serial feature-positive conditional discrimination procedure the properties of a target stimulus A are defined by the presence or not of a feature stimulus X preceding it.
J.L.O. Bueno, A.A. Scaduto
doaj
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Ensino de Leitura de Sentenças: Contribuições da Análise do Comportamento
RESUMOO paradigma da equivalência de estímulos tem sido pouco usado para estudar o ensino de leitura de sentenças. Assim, o presente estudo avaliou o efeito de um procedimento de ensino e testes de relações condicionais seguidos pelo encadeamento de ...
Verônica Bender Haydu +3 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Arbitrary conditional discriminations are difficult to obtain in non-human subjects. This study evaluates the efficacy of sample stimulus shaping procedure. Two experiments were carried out.
Ilara Reis Nogueira da Cruz +5 more
doaj
FUNCTION OF FEEDBACK AND INSTRUCTIONS PRESENCE OR ABSENCE IN DESCRIPTION ELABORATION ON CONDITIONAL DISCRIMINATION TASKS [PDF]
The function of rules and instructions to facilitate, maintain or modify the behaviour of individuals has been widely explored in a great variety of tasks.
Guerrero Radillo, Alejandra Paola +1 more
doaj

