Results 91 to 100 of about 86,978 (136)

Salidroside targeted cytosolic phospholipase A2 and regulated arachidonic acid metabolomics to attenuate atherosclerosis progression

All Life
Lipid metabolism disturbances are linked to the development of atherosclerosis (AS), with arachidonic acid (AA) and other downstream metabolites being involved. Cytosolic phospholipase A2 (cPLA2) is a key restriction enzyme in AA metabolism. Salidroside (
Qing Liao, Yihua Wang, Rong Huang, Ailu Deng, Han Xu, Wen Guo, Dan Wen, Tianqin Xia, Jiaojiao Bian, Zhengmin Xu, Chunyang Zhou   +10 more
doaj   +1 more source

Glucose Transporter 1 in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai, Zhihao Chen, Yuping Zhu, Weidong Han   +3 more
wiley   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun, Linqing Wen, Shiyun Tang, Lu Liu, Nianzhi Chen   +4 more
wiley   +1 more source

Mechanisms and Research Progress of Leech in Diabetic Ulcer Fibrosis

International Wound Journal, Volume 23, Issue 8, August 2026.
ABSTRACT Delayed wound healing is a major complication of diabetes, with its core pathological process being pathological fibrosis driven by persistent inflammation, metabolic disorders and vascular dysfunction under hyperglycemia. This process involves pathological retention of inflammatory cells, abnormal expression of pro‐fibrotic factors, and ...
Yanchun Wang, Xianglong Zheng, Huafa Que, Zhangren Yan   +3 more
wiley   +1 more source

DcH3.3 and DcNAC1 Regulate the Expression of UGT73A93 Involved in the Changes in Flower Colour and Fungal Resistance in Carnation

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4863-4877, August 2026.
ABSTRACT Carnation (Dianthus caryophyllus) contains abundant flavonoid glycosides (FGs), which are important natural functional and colour components. However, there are few reports on the modification of UDP‐glycosyltransferases (UGTs) in relation to flavonoids in carnation.
Xuhong Zhou, Qirui Xiong, Yue Zhang, Xiumei Yang, Siyuan Zhang, Yanxia Tao, Xiaomi Yang   +6 more
wiley   +1 more source

Lactic acid fermentation of papaya juice using single and mixed Lactic acid bacteria

Shipin yu jixie
Objective: Phytochemistry, microbiology, flavor and functional properties of fermented papaya juice were examined in relation to Lactobacillus plantarum (Lp), Lactobacillus rhamnosus (Lr), Lactobacillus acidophilus (La) and their mixed strains (Lp+Lr、Lp ...
ZHOU Yao, LI Juan, JIA Fengxia, HUANG Jingyu, SU Zhimin, CHEN Gang   +5 more
doaj   +1 more source

Nardosinone improves levodopa-induced dyskinesia in Parkinsonian rats through the microbiota–gut–brain axis

Scientific Reports
Levodopa-induced dyskinesia (LID) is a side effect of Parkinson’s disease (PD) treated with L-3,4-dihydroxyphenylalanine (L-DOPA). Nardosinone is the major active component of the dried root and rhizome of Nardostachys jatamansi DC, which is effective ...
Jingwen Xue, Mengmeng Liu, Yuxin Cao, Zhuangzhuang Hao, Yuqing Wang, Yu Wang, Yifan Lu, Wenxin Fan, Ge Zhang, Jinli Shi   +9 more
doaj   +1 more source

Mono-ADP-ribosylation, a MARylationmultifaced modification of protein, DNA and RNA: characterizations, functions and mechanisms

Cell Death Discovery
The functional alterations of proteins and nucleic acids mainly rely on their modifications. ADP-ribosylation is a NAD+-dependent modification of proteins and, in some cases, of nucleic acids.
Hao Wu, Anqi Lu, Jiuzhi Yuan, Yang Yu, Chongning Lv, Jincai Lu   +5 more
doaj   +1 more source

Enhanced thermostability of nattokinase by rational design of disulfide bond

Microbial Cell Factories
Nattokinase, the thrombolytically active substance in the health food natto, nevertheless, its lower thermostability restricts its use in food and pharmaceutical applications.
Kongfang Yu, Liangqi Chen, Yaolei Tang, Aixia Ma, Wenhui Zhu, Hong Wang, Xiyu Tang, Yuan Li, Jinyao Li   +8 more
doaj   +1 more source

Issue Information

MedComm, Volume 7, Issue 8, August 2026.
wiley   +2 more sources