Results 81 to 90 of about 86,978 (136)

Phenolic exudates from orchid seeds as nutrients chemically attract fungi

open access: yesJournal of Integrative Plant Biology, EarlyView.
Most orchid species require fungi for natural germination, but the molecular mechanism of this symbiosis is poorly understood. Cremastra appendiculata seeds secrete phenolic acids before fungal contact, acting as nutrient molecules to chemically attract its symbiotic fungus Coprinellus disseminatus.
Zhao Liu   +10 more
wiley   +1 more source

A Journey Between Science and the Arts: Templates for the Depiction of the Pineapple (Sixteenth to Eighteenth Centuries)

open access: yesRenaissance Studies, EarlyView.
ABSTRACT Native to America, the pineapple—Ananas comosus (L.) Merr.—delighted the Europeans who came across it. The fruit was mentioned by the voyagers and missionaries who observed and tasted it in the Americas and, from the 1500s onwards, infused reports, chronicles and natural history treatises with colour and flavour.
Teresa Nobre de Carvalho
wiley   +1 more source

Evaluation of different ecological regions for cultivation of best quality Bupleurum: a case study from Shanxi, China

open access: yesBMC Plant Biology
Bupleurum, a plant of the genus Bupleurum L. in the family Umbelliferae, is prevalent and extensively applied in traditional medicine systems across East and Southeast Asian countries for the treatment of colds, malaria, hepatitis and other diseases.
Wenli Zhang   +6 more
doaj   +1 more source

Integrated Single‐Cell RNA Sequencing and Untargeted Metabolomics Reveals β‐Elemene's Immune and Metabolic Modulation in Triple‐Negative Breast Cancer

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
In a 4T1 TNBC model, β‐elemene suppressed tumor growth and pulmonary metastasis. scRNA‐seq showed it remodeled the tumor microenvironment by reducing cancer‐associated fibroblasts, enhancing antigen presentation, and inhibiting pro‐tumorigenic ECM remodeling. Metabolomics revealed prostaglandin downregulation.
Zhiqiang Luo   +8 more
wiley   +1 more source

Regulation of emotional states by volatile herbal extracts: Multisystem physiological evidence from Rosa rugosa, Acorus tatarinowii, and Cyperus rotundus

open access: yesComplementary Therapies in Medicine
Background: Traditional aromatic herbs Rosa rugosa Thunb. (R. rugosa), Acrorus tatarinowii Schott (A. tatarinowii) and Cyperus rotundus L. (C. rotundus) have been used for emotional state regulation, yet their underlying physiological mechanisms and ...
Hui Wang   +5 more
doaj   +1 more source

CKLF‐like MARVEL transmembrane domain‐containing superfamily 8 (CMTM8) promotes Notch signalling to maintain CD8+ T cell‐ and NK cell‐dependent tumour immune escape

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 17, Page 5211-5229, September 2026.
Background and Purpose The CKLF‐like MARVEL transmembrane domain containing superfamily (CMTM) has an important role in tumour immunity. The role of CMTM8 in tumour immune microenvironment (TIME) remains unknown. The aim was to investigate the relationship between CMTM8 and antitumour immunity. Experimental Approach Lentiviral system was established to
Fanglin Li   +14 more
wiley   +1 more source

Discovery of novel coumarin derivatives as potent and orally bioavailable BRD4 inhibitors based on scaffold hopping

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2019
The bromodomain and extra-terminal (BET) bromodomains, particularly BRD4, have been identified as promising therapeutic targets in the treatment of many human disorders such as cancer, inflammation, obesity, and cardiovascular disease.
Zhimin Zhang   +7 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, Volume 16, Issue 8, Page 1459-1476, August 2026.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Flowers as Dishes With Cultural Flavors: Nutritional Profiles and Taste Characteristics of Four Edible Flower Species in Yunnan, China

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
This graphical abstract highlights the nutritional profiles and taste characteristics of four edible flower species, Musella lasiocarpa (Franch.) C. Y. Wu ex H. W. Li, Plumeria rubra L. “Acutifolia,” Stephanotis volubilis (L.f.) S.Reuss, Liede & Meve (syn. Dregea volubilis (L. f.) Benth. ex Hook.
Qing Zhang   +8 more
wiley   +1 more source

A Pharmacogenomics‐Guided Antihypertensive Strategy for Blood Pressure Reduction in Rural China: A Cluster‐Randomized Controlled Trial

open access: yesHealth Care Science, Volume 5, Issue 4, Page 353-363, August 2026.
This manuscript reports the findings from the Pharmacogenomic‐guided Antihypertensive Strategy Trial study amidst the deteriorating blood pressure control observed globally during the COVID‐19 pandemic. A pharmacogenomics‐guided strategy achieved a 98.4% blood pressure control rate at 4 weeks in rural China.
Wangjun Qin   +22 more
wiley   +1 more source

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