Results 101 to 110 of about 202,854 (222)

A Novel Mechanism of Salvianolic Acid B in Postmyocardial Infarction Cardiac Protection: PHB1‐Driven Raf‐ERK Pathway Activation Promotes Cardiomyocyte Mitosis

MedComm, Volume 7, Issue 5, May 2026.
SalB binds to the C‐terminal of PHB1/2 heterodimer, inducing a conformational change that enhances Raf‐ERK pathway activation via Akt‐mediated phosphorylation, thereby promoting cardiomyocyte mitosis. ABSTRACT Heart failure (HF) following myocardial infarction remains a leading cause of global morbidity and mortality, necessitating novel therapeutic ...
Ce Cao, Bo Ma, Jian Zhang, Lili Yang, Zixin Liu, Haoran Li, Jianshu Song, Keer Zhang, Lei Li, Jianhua Fu, Jianxun Liu   +10 more
wiley   +1 more source

Lipidomics coupled with pathway analysis characterizes serum metabolic changes in response to potassium oxonate induced hyperuricemic rats

Lipids in Health and Disease, 2019
Background Hyperuricemia as a metabolic disease is usually associated with lipid metabolic disorder. The purpose of this study is to identify potential lipid biomarkers and provide the evidence for the relationship between hyperuricemia and lipid-related
Fei Yang, Mingyu Liu, Nankun Qin, Shuangshuang Li, Mengqi Yu, Chengxiang Wang, Qun Ma   +6 more
doaj   +1 more source

Interpreting materia medica. A case study on Ioannes Archiatrus. [PDF]

Wellcome Open Res, 2023
Zipser B, Lardos A, Lazarou R, Allkin R, Nesbitt M, Scott AC.   +5 more
europepmc   +1 more source

Discovery of novel coumarin derivatives as potent and orally bioavailable BRD4 inhibitors based on scaffold hopping

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
The bromodomain and extra-terminal (BET) bromodomains, particularly BRD4, have been identified as promising therapeutic targets in the treatment of many human disorders such as cancer, inflammation, obesity, and cardiovascular disease.
Zhimin Zhang, Lili Gu, Beibei Wang, Wenhai Huang, Yanmin Zhang, Zhen Ma, Shenxin Zeng, Zhengrong Shen   +7 more
doaj   +1 more source

The Decline and Fall of Materia Medica and the Rise of Pharmacology and Therapeutics in Veterinary Medicine. [PDF]

Front Vet Sci, 2021
Lees P, Bäumer W, Toutain PL.
europepmc   +1 more source

Old School Catalog 1905-06, Chicago College of Dental Surgery [PDF]

, 1905
https://scholar.valpo.edu/oldschoolcatalogs/1033/thumbnail ...
Valparaiso University
core   +2 more sources

Deconstructing Masculinity: A Mixed‐Methods Exploration of Health Access and Legal Implications Among Middle‐Aged Men in Yaoundé, Cameroon

Sexuality, Gender &Policy, Volume 9, Issue 2, May 2026.
ABSTRACT Masculinity significantly influences men's health‐seeking behaviors, yet its intersection with legal frameworks and healthcare access in Sub‐Saharan Africa remains underexplored. This mixed‐methods study investigates how gender norms and structural barriers influence healthcare experiences among 60 middle‐aged men (aged 30–60 years) in Yaoundé,
Ikekhwa Albert Ikhile, Carlos Joel Tchawouo Mbiada   +1 more
wiley   +1 more source

Old School Catalog 1912-13, Chicago College of Dental Surgery [PDF]

, 1912
https://scholar.valpo.edu/oldschoolcatalogs/1012/thumbnail ...
Valparaiso University
core   +6 more sources

Once again on the Empress Zoe: Women, dermatology, cosmetics, and materia medica (medical matter) in the ancient world. [PDF]

J Cosmet Dermatol, 2023
Cilione M, Cavarra B, Gazzaniga V.
europepmc   +1 more source

Old School Catalog 1914-15, Chicago College of Dental Surgery [PDF]

, 1914
https://scholar.valpo.edu/oldschoolcatalogs/1115/thumbnail ...
Valparaiso University
core   +2 more sources