Results 101 to 110 of about 510,075 (275)

Macrophage‐targeted cerium‐tannic acid metal‐polyphenol framework nanoenzyme promotes in situ heart valves regeneration through adaptive immunomodulation

BMEMat, EarlyView.
A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song, Yunlong Wu, Xing Chen, Yafei Liu, Mengna Dong, Jiawei Shi, Xichi Wang, Nianguo Dong, Weihua Qiao, Qin Wang   +9 more
wiley   +1 more source

Integrating network pharmacology and animal experimental validation to investigate the action mechanism of oleanolic acid in obesity

Journal of Translational Medicine
Background Obesity, a condition associated with the development of widespread cardiovascular disease, metabolic disorders, and other health complications, has emerged as a significant global health issue.
Tianfeng Liu, Jiliang Wang, Ying Tong, Lele Wu, Ying Xie, Ping He, Shujue Lin, Xuguang Hu   +7 more
doaj   +1 more source

Comparison of veterinary drugs and veterinary homeopathy: part 1 [PDF]

, 2017
For many years after its invention around 1796, homeopathy was widely used in people and later in animals. Over the intervening period (1796-2016) pharmacology emerged as a science from Materia Medica (medicinal materials) to become the mainstay of ...
AABEL, AHN, ANICK, BEKELMAN, BELL, BELL, BELL, BELLAVITE, BELON, BELON, BOERICKE, CALABRESE, CALABRESE, CALABRESE, CALABRESE, CAMPBELL, CANFIELD, CARTWRIGHT, CHAMBERS, CHAMBERS, CHAN, CHAPMAN, CHIKRAMANE, CONZEMIUS, COWAN, CROSKERRY, CROSKERRY, CUCHERAT, CUNNINGHAM, DAVENAS, DI GIROLAMO, DOEHRING, DOUST, EASTERBROOK, ELIA, ENNIS, ERNST, FLOWER, FRASER, GARTLEHNER, GAY, GODWIN, GOLDACRE, GREGORY, GREGORY, GREGORY, GRIMES, GRUEN, GRUEN, HAHNEMANN, HARTMAN, HEKTOEN, HEKTOEN, HIRST, HOVI, HRÓBJARTSSON, IOANNIDIS, IOANNIDIS, IOANNIDIS, IOANNIDIS, IOANNIDIS, JACOBS, JADAD, JONAS, JONAS, KAHANB, KAHNEMAN, KAYNE, KAYNE, KOHN, LEE, LEES, LEES, LEES, LEXCHIN, LILLEY, LINDE, MADDOX, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATUTE, MCGAURAN, MCKENZIE, MILAZZO, MILGROM, MONTAGNIER, NICOLAI, OWEN, OWEN, OWEN, OWEN, OXTOBY, PAULSON, PINTO, PRASAD, RAO, REILLY, REY, REY, RILEY, ROY, RUDOLF, SACKETT, SAPOSNIK, SARGEANT, SARGEANT, SCHULZ, SHANG, SHAW, SHERR, SHOJANIA, SMITH, SMITH, STERN, TEMGIRE, TOUTAIN, VAN WIJK, VANDENBERG, VIERA, WHITEHEAD, WHITING, WORLD HEALTH, ZOONOSES AND PUBLIC   +128 more
core   +5 more sources

Physicochemical Properties and Antioxidant Activity of Apocynum Honey in Different Regions of Xinjiang

Food Chemistry International, EarlyView.
ABSTRACT In this study, honey produced from Apocynum venetum L. was collected from BC (Bachu County), SY (Shaya County), and YL (Yuli County) in Xinjiang. The basic physical and chemical properties of the honey, and the contents of total phenols, total flavonoids, and amino acids were analyzed, and 16 types of polyphenols were quantified using triple ...
Na Zhang, Jingjing Lv, Ruili Zhang, Qinghua Jia, Tiantian Jian, Yawen Li   +5 more
wiley   +1 more source

Il contributo peritale e il ruolo dell’esperto [PDF]

, 2019
Il contributo esplora le problematiche poste dalla metabolizzazione della prova scientifica nell’accertamento penale della responsabilità per colpa medica, alla luce del quadro complessivo ridisegnato dalla l. n. 24 del 2017 (c.d.
DI CHIARA GIUSEPPE
core  

Peach Kernel Oil Modulates Lipid Metabolism Disorder in ApoEa CRISPR/Cas9 Gene‐Disrupted Zebrafish

Food Frontiers, EarlyView.
In this study, we used CRISPR/Cas9 gene editing technology to establish a lipid metabolism disorder model of ApoEa mutant zebrafish. We applied peach kernel oil to this model and studied the mechanism of peach kernel oil regulating lipid disorder in combination with transcriptomics.
Lei Xia, Yuemi Mo, Yuntian Duan, Hu Liang, Yulu Li, Wanruo Wan, Minghuang Luo, Qianhua Li, Xueni Wang, Qing Chen, Zhengcai Du, Xiaotao Hou, Fan Zhang, Jiagang Deng, Erwei Hao   +14 more
wiley   +1 more source

Volatile Oil From Acorus Gramineus Rhizoma Synergizes with Crebanine to Alleviate Oxidative Stress and Endoplasmic Reticulum Stress in Myocardial Ischemia-Reperfusion Injury by Suppressing GRP78-PERK/ATF6-CHOP and MAPK-NF-κB-TNF-α Signaling Pathways

Journal of Inflammation Research
Lichun Zha,1,2,* Lili Cui,1,3,* Jiahua Mei,1,4,* Juan Pu,1,3 Jiaxu Hao,1,4 Xiao Fan,1,4 Hongyuan Wang,1,3 Heng Fang,1 Yunshu Ma1,3,4 1School of Chinese Materia Medica of Yunnan University of Traditional Chinese Medicine, Kunming ...
Zha L, Cui L, Mei J, Pu J, Hao J, Fan X, Wang H, Fang H, Ma Y   +8 more
doaj  

Regulation of emotional states by volatile herbal extracts: Multisystem physiological evidence from Rosa rugosa, Acorus tatarinowii, and Cyperus rotundus

Complementary Therapies in Medicine
Background: Traditional aromatic herbs Rosa rugosa Thunb. (R. rugosa), Acrorus tatarinowii Schott (A. tatarinowii) and Cyperus rotundus L. (C. rotundus) have been used for emotional state regulation, yet their underlying physiological mechanisms and ...
Hui Wang, Dan Qin, Xinjie Shi, Menghan Fan, Wenyan Li, Yun Wang   +5 more
doaj   +1 more source

Discovery of novel coumarin derivatives as potent and orally bioavailable BRD4 inhibitors based on scaffold hopping

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
The bromodomain and extra-terminal (BET) bromodomains, particularly BRD4, have been identified as promising therapeutic targets in the treatment of many human disorders such as cancer, inflammation, obesity, and cardiovascular disease.
Zhimin Zhang, Lili Gu, Beibei Wang, Wenhai Huang, Yanmin Zhang, Zhen Ma, Shenxin Zeng, Zhengrong Shen   +7 more
doaj   +1 more source

Isorhamnetin Alleviates Renal Fibrosis Induced by Renal Tubular Epithelial Cell Senescence Via Inhibition of the IL‐6/IL‐6R Signaling Pathway

iMetaMed, EarlyView.
IL‐6 from RTECs upregulates TGF‐β in macrophages, promoting fibroblast transdifferentiation. Isorhamnetin inhibits this effect. ABSTRACT Chronic kidney disease (CKD) is a major global health issue. Kidney fibrosis is a key mechanism leading to end‐stage renal disease.
Weifei Liang, Xiangqiu Chen, Tao Wu, Xichun Zheng, Shaohua Zeng, Qingchun Zhou, Wen Ma, Hao Lin, Donglin Sun   +8 more
wiley   +1 more source