Results 111 to 120 of about 188,259 (274)

Interpreting materia medica. A case study on Ioannes Archiatrus. [PDF]

open access: yesWellcome Open Res, 2023
Zipser B   +5 more
europepmc   +1 more source

Il contributo peritale e il ruolo dell’esperto [PDF]

open access: yes, 2019
Il contributo esplora le problematiche poste dalla metabolizzazione della prova scientifica nell’accertamento penale della responsabilità per colpa medica, alla luce del quadro complessivo ridisegnato dalla l. n. 24 del 2017 (c.d.
DI CHIARA GIUSEPPE
core  

The clarification of two hydroxylation steps in the conversion of cholesterol to OSW‐1 in Ornithogalum saundersiae

open access: yesPlant Biotechnology Journal, EarlyView.
Summary OSW‐1 is a cholestane saponin uniquely produced in Ornithogalum saundersiae and exhibits a potential antitumor activity. The enzymes responsible for OSW‐1 biosynthesis in O. saundersiae, however, remain unclear. Herein, cholesterol was confirmed to be the precursor of OSW‐1 using stable‐isotope labeling method.
Shu‐Yue Zhang, Jian‐Qiang Kong
wiley   +1 more source

Evaluation of different ecological regions for cultivation of best quality Bupleurum: a case study from Shanxi, China

open access: yesBMC Plant Biology
Bupleurum, a plant of the genus Bupleurum L. in the family Umbelliferae, is prevalent and extensively applied in traditional medicine systems across East and Southeast Asian countries for the treatment of colds, malaria, hepatitis and other diseases.
Wenli Zhang   +6 more
doaj   +1 more source

Lipidomics coupled with pathway analysis characterizes serum metabolic changes in response to potassium oxonate induced hyperuricemic rats

open access: yesLipids in Health and Disease, 2019
Background Hyperuricemia as a metabolic disease is usually associated with lipid metabolic disorder. The purpose of this study is to identify potential lipid biomarkers and provide the evidence for the relationship between hyperuricemia and lipid-related
Fei Yang   +6 more
doaj   +1 more source

Single‐cell sequencing and mass spectrometry imaging reveal the multicellular compartmentalization map of plant triterpenes: A ginsenoside in Panax ginseng example

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Revealing the multicellular compartmentalization map is crucial for plant breeding and metabolism regulation. Despite the importance of triterpenes as active compounds, there has been no report on their biosynthetic multicellular mapping. In this study, ginsenosides are used as an example to reveal the multicellular compartmentalization map of ...
Rubing Wang   +8 more
wiley   +1 more source

Discovery of novel coumarin derivatives as potent and orally bioavailable BRD4 inhibitors based on scaffold hopping

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2019
The bromodomain and extra-terminal (BET) bromodomains, particularly BRD4, have been identified as promising therapeutic targets in the treatment of many human disorders such as cancer, inflammation, obesity, and cardiovascular disease.
Zhimin Zhang   +7 more
doaj   +1 more source

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