Results 61 to 70 of about 500,943 (335)

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

open access: yesAdvanced Science, EarlyView.
The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao   +11 more
wiley   +1 more source

Museum of Materia Medica(Research Center for Ethnomedicine) [PDF]

open access: yes, 2006
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されまし
出口 鳴美, 小松 かつ子
core   +1 more source

Report on Materia Medica [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1884
n ...
openaire   +2 more sources

7‐Ketodeoxycholic Acid Promotes Colonic Mucosal Healing by Inducing Calcium Release from Endoplasmic Reticulum via the TGR5‐IP3R Pathway

open access: yesAdvanced Science, EarlyView.
7‐KDCA functions by driving intestinal epithelial cell migration through induction of calcium release from the endoplasmic reticulum. The findings emphasize a previously unrecognized property of 7‐KDCA in regulating cell migration, a required process for effective epithelial restitution and repair that is particularly critical for patients with UC to ...
Jing Zhang   +9 more
wiley   +1 more source

Medizintheoretische und wissenschaftshistorische Perspektiven einer Revision der Materia medica homoeopathica [PDF]

open access: yes, 2010
In der Homöopathie ist das, was an Patienten und Arzneimittelprüfern beobachtet wird, nicht trivial. Symptome sind hier keine Messwerte, sondern ihre Wahrnehmung, Aufzeichnung und praktische Verwertung sind abhängig von der jeweils zugrunde gelegten ...
Schmidt, Josef M.
core   +1 more source

Inhaling Eugenol Inhibits NAFLD by Activating the Hepatic Ectopic Olfactory Receptor Olfr544 and Modulating the Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang   +15 more
wiley   +1 more source

Zein nanoparticles as nontoxic delivery system for maytansine in the treatment of non-small cell lung cancer

open access: yesDrug Delivery, 2020
Purpose Maytansine (DM1) is a potent anticancer drug and limited in clinical application due to its poor water solubility and toxic side effects. Zein is widely used in nano drug delivery systems due to its good biocompatibility.
Xianglong Yu   +8 more
doaj   +1 more source

Steric‐Adaptive Biocatalysis: Imine Reductase‐Mediated Dynamic Kinetic Resolution for Atroposelective Synthesis of Hindered Biaryl Amines

open access: yesAdvanced Science, EarlyView.
An unusual IRED platform is reported, enabling efficient DKR via reductive amination without any evolutionary engineering. The system accommodates extremely sterically demanding substrates, including naphthyl and quinoline derivatives, delivering naphthyl‐aryl and quinoline‐aryl amine atropisomers with excellent efficiency and stereocontrol (over 80 ...
Zhichao Ni   +7 more
wiley   +1 more source

Beneficial effects of crude extract of Eupatorium lindleyanum DC. in hyperlipidemia and atherosclerosis

open access: yesBiotechnology & Biotechnological Equipment, 2016
The aim of this study was to evaluate the effects of crude extract of Eupatorium lindleyanum DC. (CEEL) on reducing hyperlipidemia and preventing atherosclerosis induced with a high cholesterol diet (HCD) in rabbits.
Xing Zhou   +6 more
doaj   +1 more source

ANTI-INFLAMMATORY AND ANTI-ALLERGIC FEATURES OF ANTIBODIES TO HISTAMINE IN RELEASE-ACTIVE FORM: REVIEW OF EXPERIMENTAL AND CLINICAL RESEARCHES

open access: yesДетские инфекции (Москва), 2015
Preclinical and clinical studies of medical preparations (rengalin, ergoferon) containing release-active (P-A) antibodies to histamine confirmed their ability to provide anti-inflammatory and anti-allergic effect.
E. S. Zhavbert   +2 more
doaj   +1 more source

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