Results 101 to 110 of about 1,336,966 (305)

Genetics and Material Culture Support Repeated Expansions into Paleolithic Eurasia from a Population Hub Out of Africa. [PDF]

Genome Biol Evol, 2022
Vallini L, Marciani G, Aneli S, Bortolini E, Benazzi S, Pievani T, Pagani L.   +6 more
europepmc   +1 more source

The Single-Artifact Approach to Material Culture Studies: A Perspective from New Zealand

, 2011
In this chapter I present an approach to material culture studies, from the perspective of a Pakeha/European New Zealander, which draws upon my knowledge and understanding of nga rakau korero, the talking sticks of the indigenous Maori people of New ...
Smith, J
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

THE EARLIEST EVIDENCE OF THE MANUFACTURING OF SOLUTIONS AND VISCOPLASTIC MIXTURES FROM PAINT PIGMENTS ON THE RUSSIAN PLAIN IN THE MIDDLE PALEOLITHIC

Нижневолжский археологический вестник
The article presents the results of studying a series of small individual pigment particles discovered in the cultural layer of the Chelyuskinets II site, which is part of the Lower Volga Middle Paleolithic group together with the Eurasian ...
Maria Zheltova, Maria Komagorova, Yulia Anisovets, Vladislav Zhitenev, Darya Ulyanova, Redzhep Kurbanov, Ksenia Stepanova, Anton Anoykin, Yaroslav Ivanov, Vasilisa Smolkina, Evgeniy Kazakov, Stanislav Remizov, Aleksander Otcherednoy   +12 more
doaj   +1 more source

Review of the research programme on the Mortella III wreck (2010-2020, Corsica, France): A contribution to the knowledge of the Mediterranean naval architecture and material culture of the Renaissance. [PDF]

Open Res Eur, 2022
Cazenave de la Roche A, Ciacchella F, Langenegger F, Guérout M, Milanese M, Crespo Solana A.   +5 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Interpreting Environmental History through Material Culture

, 1997
In an exhibition called UnEarthing the Secret Life of Stuff: Americans and the Environment, the Strong Museum uses nineteenth- and twentieth-century domestic artifacts to ntroduce its audience to the subject of environmental history.
Clarke-Hazlett, Christopher
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Yakov A. Sher (1931–2019): Milestones of Academic Career

СибСкрипт
Professor Yakov A. Sher (1931–2019), Doctor of History, was a world-famous specialist in prehistoric art. This research relied on the archives of the Institute for Material Culture History, the State Hermitage Museum, and the Kemerovo State University to
Lyudmila Yu. Kitova, Daria Yu. Hookk, Alexey V. Fribus   +2 more
doaj   +1 more source